4-Phenyl-Butylamine

4-Phenyl-Butylamine

SCHEMBL6853029

CC(C)NCc1ccccc1.NCCCCc1ccccc1

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.63
SIGMAR1 Q99720 11/20 0.49
HTR2A P28223 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Putrescine SCHEMBL8006412 0.93 SIGMAR1 (0.53) MAOASIGMAR1
SCHEMBL5950278 0.86 MAOA (0.46) MAOASIGMAR1HTR2A
SCHEMBL22899588 0.82 SIGMAR1 (0.65) SIGMAR1
SCHEMBL143708 0.82 SIGMAR1 (0.65) SIGMAR1
Hydrochloric Acid SCHEMBL1331235 0.80 SIGMAR1 (0.63) SIGMAR1
Bromide SCHEMBL1331742 0.80 SIGMAR1 (0.63) SIGMAR1
Ammonia Solution, Strong SCHEMBL15917374 0.80 SIGMAR1 (0.63) SIGMAR1
4-Phenyl-Butylamine SCHEMBL132472 0.80 MAOA (1.00) MAOASIGMAR1HTR2A
Methyl Alcohol SCHEMBL29261100 0.78 SIGMAR1 (0.61) SIGMAR1
SCHEMBL23070514 0.78 MAOA (0.95) MAOASIGMAR1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0959975-B1 NOVEL AFFINITY LIGANDS AND THEIR USE NOVO NORDISK AS (DK) 2004-12-29 EP disclosed
CN-1089617-C Novel attinity ligands and their use NOVO NORDISK AS (DK) 2002-08-28 CN disclosed
US-6117996-A COMPLEXING; SEPARATION; PURIFICATION OF PROTEINS NOVO NORDISK A/S (DK) 2000-09-12 US disclosed
CN-1200680-A Novel attinity ligands and their use NOVO NORDISK AS (DK) 1998-12-02 CN disclosed