SCHEMBL6853273

SCHEMBL6853273

O=C(O)c1ccccc1ONc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.53
HSD17B10 Q99714 6/20 0.53
HPGD P15428 5/20 0.53
ALDH1A1 P00352 9/20 0.52
ESR1 P03372 1/20 0.52
ITGB3 P05106 1/20 0.52
ITGA2B P08514 1/20 0.52
HMGB1 P09429 1/20 0.52
TSHR P16473 1/20 0.52
GGT1 P19440 1/20 0.52
PTGS1 P23219 1/20 0.52
PTGS2 P35354 1/20 0.52
BLM P54132 1/20 0.52
NAPRT Q6XQN6 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
USP2 O75604 1/20 0.50
PDE3A Q14432 1/20 0.50
MAPT P10636 1/20 0.50
KMT2A Q03164 3/20 0.49
HTT P42858 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30255502 1.00 KDM4E (0.53) KDM4EHSD17B10HPGDALDH1A1ESR1
SCHEMBL9770977 0.90 GAA (0.48) KDM4EHSD17B10HPGDALDH1A1ESR1
SCHEMBL944403 0.85 LMNA (0.49) KDM4EHSD17B10HPGDALDH1A1ESR1
SCHEMBL28027699 0.84 ALDH1A1 (0.47) KDM4EHSD17B10HPGDALDH1A1ESR1
SCHEMBL942870 0.81 ABCB1 (0.47) KDM4EHSD17B10ALDH1A1TSHRUSP2
SCHEMBL3460086 0.79 ALDH1A1 (0.43) KDM4EHSD17B10HPGDALDH1A1TSHR
SCHEMBL2493557 0.78 KDM4E (0.55) KDM4EHSD17B10HPGDALDH1A1ESR1
SCHEMBL7111180 0.78 KDM4E (0.55) KDM4EHSD17B10HPGDALDH1A1ESR1
SCHEMBL1982429 0.77 KDM4E (0.53) KDM4EHSD17B10HPGDALDH1A1ESR1
SCHEMBL38660686 0.76 KDM4E (0.61) KDM4EHSD17B10HPGDALDH1A1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117384259-A Cell penetrating peptides based on influenza virus M2 proteins 中国医学科学院基础医学研究所 2024-01-12 CN claimed
CN-112912386-B Cell penetrating peptides based on influenza virus M2 proteins 中国医学科学院基础医学研究所 2023-10-20 CN claimed
CN-112912386-A Cell penetrating peptide based on influenza virus M2 protein 中国医学科学院基础医学研究所 2021-06-04 CN claimed
US-20030105066-A1 Nitrate salts of antimicrobial agents NICOX S.A. (FR) 2003-06-05 US claimed
EP-1253924-A1 NITRATE SALTS OF ANTIMICROBIAL AGENTS NICOX S.A. (FR) 2002-11-06 EP claimed
WO-2001054691-A1 NITRATE SALTS OF ANTIMICROBIAL AGENTS NICOX, S.A. (FR) 2001-08-02 WO claimed
EP-0046270-B1 NOVEL DERIVATIVES OF BIO-AFFECTING PHENOLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITION CONTAINING THEM INTERx RESEARCH CORPORATION (US) 1986-05-21 EP claimed
CN-113861268-B Cell penetrating peptides and methods of making and using the same 恩特拉达治疗学股份有限公司 2025-04-01 CN disclosed
CN-117866128-A Functionalization C 4 to 5 Olefin polymer and lubricant composition containing the same 英菲诺姆国际有限公司 2024-04-12 CN disclosed
CN-117866042-A Disulfide-containing cell penetrating peptides and methods of making and using the same 俄亥俄州国家创新基金会 2024-04-12 CN disclosed
CN-117597327-A Pharmaceutical preparation 第一波动生物制药股份有限公司 2024-02-23 CN disclosed
CN-110114075-B Disulfide-containing cell penetrating peptides and methods of making and using the same 俄亥俄州国家创新基金会 2024-01-12 CN disclosed
CN-117384259-A Cell penetrating peptides based on influenza virus M2 proteins 中国医学科学院基础医学研究所 2024-01-12 CN disclosed
US-9089388-B2 Oral appliance for delivery of medicaments and/or other substances EMANATE BIOMEDICAL INC. 2015-07-28 US disclosed
US-6794372-B2 QUINOLONE ANTIBIOTIC VIRICIDES, FUNGICIDES, AND BACTERICIDES NICOX S.A. (FR) 2004-09-21 US disclosed
US-20030105066-A1 Nitrate salts of antimicrobial agents NICOX S.A. (FR) 2003-06-05 US disclosed
EP-1253924-A1 NITRATE SALTS OF ANTIMICROBIAL AGENTS NICOX S.A. (FR) 2002-11-06 EP disclosed
EP-1230917-A1 Invasomes for the therapy of illnesses, their manufacture and use Vectron Therapeutics AG (DE) 2002-08-14 EP disclosed
WO-2001054691-A1 NITRATE SALTS OF ANTIMICROBIAL AGENTS NICOX, S.A. (FR) 2001-08-02 WO disclosed
US-4036951-A SUNSCREEN AGENTS SYNERGISTICS, INC. (US) 1977-07-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030105066-A1 Nitrate salts of antimicrobial agents NOS1, NOS3, NOS2 KDM4E 4352/4885HSD17B10 4408/4885HPGD 1399/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.