SCHEMBL22040159

SCHEMBL22040159

CCOC(=O)c1ncn(CC)n1

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
JMJD6 Q6NYC1 2/20 0.45
KMT2A Q03164 2/20 0.41
MAPT P10636 2/20 0.40
CYP1A2 P05177 1/20 0.40
TSHR P16473 1/20 0.39
ADORA2A P29274 1/20 0.39
ADORA1 P30542 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
ALDH1A1 P00352 1/20 0.38
ADORA3 P0DMS8 2/20 0.38
HTT P42858 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6855286 0.88 KMT2A (0.40) JMJD6KMT2AMAPTCYP1A2TSHR
SCHEMBL4670651 0.85 KMT2A (0.39) JMJD6KMT2AMAPTCYP1A2TSHR
SCHEMBL4784720 0.84 NOTUM (0.46) JMJD6KMT2ACYP1A2NPC1RAB9A
SCHEMBL6849821 0.83 LMNA (0.40) JMJD6KMT2AMAPTCYP1A2ADORA2A
SCHEMBL9461194 0.81 JMJD6 (0.44) JMJD6KMT2AMAPTCYP1A2TSHR
SCHEMBL1719033 0.81 ALDH1A1 (0.56) MAPTTSHRSMN1; SMN2ALDH1A1
SCHEMBL6855922 0.81 TBXAS1 (0.37) JMJD6KMT2AMAPTADORA2AADORA1
SCHEMBL29111665 0.79 KMT2A (0.41) JMJD6KMT2AMAPTCYP1A2TSHR
SCHEMBL29446057 0.78 ALDH1A1 (0.36) JMJD6KMT2AMAPTADORA2AADORA1
SCHEMBL6858064 0.78 TBXAS1 (0.39) KMT2ATSHRNPC1RAB9AADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11591335-B2 Bicyclic pesticidal compounds BASF SE (DE) 2023-02-28 US disclosed
US-20200165255-A1 Bicyclic Pesticidal Compounds BASF SE (DE) 2020-05-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200165255-A1 Bicyclic Pesticidal Compounds DDT, ACHE, CYCS JMJD6 3337/4885KMT2A 2502/4885MAPT 3539/4885
US-11591335-B2 Bicyclic pesticidal compounds DDT, ACHE, CYCS JMJD6 3337/4885KMT2A 2502/4885MAPT 3539/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.