Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | JMJD6 | Q6NYC1 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22040159 | 0.88 | JMJD6 (0.45) | KMT2AMAPTCYP1A2JMJD6ADORA2A | |
| SCHEMBL4670651 | 0.84 | KMT2A (0.39) | KMT2AMAPTCYP1A2JMJD6ADORA2A | |
| SCHEMBL7464070 | 0.83 | ADRB3 (0.46) | KMT2AMAPTL3MBTL1 | |
| SCHEMBL6849821 | 0.81 | LMNA (0.40) | KMT2AMAPTCYP1A2JMJD6ADORA2A | |
| SCHEMBL9461194 | 0.79 | JMJD6 (0.44) | KMT2AMAPTCYP1A2JMJD6ADORA2A | |
| SCHEMBL6855922 | 0.79 | TBXAS1 (0.37) | KMT2AMAPTJMJD6ADORA2AADORA1 | |
| SCHEMBL1719033 | 0.79 | ALDH1A1 (0.56) | MAPTTSHRALDH1A1KDM4E | |
| SCHEMBL29111665 | 0.78 | KMT2A (0.41) | KMT2AMAPTCYP1A2JMJD6ADORA2A | |
| SCHEMBL29446057 | 0.77 | ALDH1A1 (0.36) | KMT2AMAPTJMJD6ADORA2AADORA1 | |
| SCHEMBL6858064 | 0.77 | TBXAS1 (0.39) | KMT2ATSHRADORA3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6831177-B1 | Preparation of their intermediates, 2-acyl-5-benzylfuran derivatives and 1,2,4-triazole-3- carboxylic acid ester derivatives | SHIONOGI & CO., LTD. (JP) | 2004-12-14 | — | — | US | disclosed |
| EP-1186599-A1 | NOVEL PROCESSES FOR THE PREPARATION OF SUBSTITUTED PROPENONE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 2002-03-13 | — | — | EP | disclosed |