SCHEMBL6854263

SCHEMBL6854263

C=Cc1c(Cl)cccc1Cl.C=Cc1ccc(C)cc1Cl

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.47
GABRA1 P14867 2/20 0.41
GABRG2 P18507 2/20 0.41
GABRB3 P28472 2/20 0.41
TDP1 Q9NUW8 2/20 0.40
TP53 P04637 1/20 0.40
KMT2A Q03164 3/20 0.35
MAPT P10636 3/20 0.35
MEN1 O00255 2/20 0.35
ALOX12 P18054 1/20 0.35
HTT P42858 1/20 0.35
LMNA P02545 1/20 0.35
HPGD P15428 1/20 0.35
RAB9A P51151 3/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
NQO2 P16083 1/20 0.32
ACHE P22303 2/20 0.32
PLA2G1B P04054 1/20 0.32
ATG4B Q9Y4P1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11852191 0.89 GABRA1 (0.44) ALDH1A1GABRA1GABRG2GABRB3TDP1
SCHEMBL139560 0.87 GABRA1 (0.50) ALDH1A1GABRA1GABRG2GABRB3TDP1
SCHEMBL17353953 0.82 ALDH1A1 (0.50) ALDH1A1GABRA1GABRG2GABRB3TDP1
SCHEMBL181965 0.77 ALDH1A1 (0.55) ALDH1A1TDP1KMT2AMAPTMEN1
SCHEMBL27920138 0.74 ALDH1A1 (0.52) ALDH1A1TDP1KMT2AMAPTMEN1
SCHEMBL1207128 0.73 ALDH1A1 (0.62) ALDH1A1TDP1KMT2AMAPTMEN1
SCHEMBL589904 0.72 TP53 (0.34) ALDH1A1TDP1TP53KMT2ALMNA
SCHEMBL16021003 0.72 ALDH1A1 (0.62) ALDH1A1TDP1TP53KMT2AMAPT
SCHEMBL8363460 0.71 ALDH1A1 (0.44) ALDH1A1TDP1TP53KMT2AMEN1
SCHEMBL9253034 0.71 ALDH1A1 (0.48) ALDH1A1GABRA1GABRG2GABRB3TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6794419-B2 Method for recycling the resin mold SUZUKA FUJI XEROX CO., LTD. (JP) 2004-09-21 US disclosed