Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20814123 | 0.95 | KDM4E (0.35) | KDM4ETSHRRECQLTDP1 | |
| SCHEMBL19149109 | 0.90 | ALDH1A1 (0.38) | KDM4ETSHRRECQLTDP1 | |
| SCHEMBL1446865 | 0.89 | KDM4E (0.38) | KDM4ETSHRRECQLTDP1 | |
| SCHEMBL6260966 | 0.89 | KDM4E (0.38) | KDM4ETSHRRECQLTDP1 | |
| SCHEMBL21531904 | 0.89 | TSHR (0.32) | KDM4ETSHR | |
| Edetol SCHEMBL48412 | 0.87 | TSHR (0.39) | KDM4ETSHRRECQLTDP1 | |
| Edetol SCHEMBL2803498 | 0.87 | TSHR (0.39) | KDM4ETSHRRECQLTDP1 | |
| SCHEMBL17351938 | 0.84 | ALDH1A1 (0.41) | KDM4ETSHRRECQLTDP1 | |
| SCHEMBL18427271 | 0.84 | ALDH1A1 (0.41) | KDM4ETSHRRECQLTDP1 | |
| Edetol SCHEMBL20942798 | 0.84 | KDM4E (0.38) | KDM4ETSHRRECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2566442-B1 | COMPOSITIONS COMPRISING EXTRACTS OF SOUTHERNWOOD AND AN AMINE COMPOUND | JOHNSON & JOHNSON CONSUMER INC (US) | 2019-10-30 | — | — | EP | disclosed |
| US-8834943-B2 | Compositions containing amines and use thereof | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2014-09-16 | — | — | US | disclosed |
| US-8834943-B2 | Compositions containing amines and use thereof | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2014-09-16 | — | — | US | disclosed |
| US-8722113-B2 | Compositions comprising extracts of southernwood and an amine compound | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2014-05-13 | — | — | US | disclosed |
| US-8722113-B2 | Compositions comprising extracts of southernwood and an amine compound | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2014-05-13 | — | — | US | disclosed |
| EP-2316411-B1 | Compositions comprising a skin-lightening resorcinol and a skin darkening agent | JOHNSON & JOHNSON CONSUMER (US) | 2014-02-12 | — | — | EP | disclosed |
| US-8344031-B2 | Compositions for the treatment of signs of aging | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2013-01-01 | — | — | US | disclosed |
| US-8344031-B2 | Compositions for the treatment of signs of aging | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2013-01-01 | — | — | US | disclosed |
| US-20120276226-A1 | COMPOSITIONS COMPRISING EXTRACTS OF SOUTHERNWOOD AND AN AMINE COMPOUND | KENVUE BRANDS LLC | 2012-11-01 | — | — | US | disclosed |
| US-20120276226-A1 | COMPOSITIONS COMPRISING EXTRACTS OF SOUTHERNWOOD AND AN AMINE COMPOUND | KENVUE BRANDS LLC | 2012-11-01 | — | — | US | disclosed |
| EP-2135622-A2 | Compositions for providing an analgesic effect to the skin | Johnson & Johnson Consumer Companies, Inc. (US) | 2009-12-23 | — | — | EP | disclosed |
| US-20090292027-A1 | COMPOSITIONS FOR THE TREATMENT OF SIGNS OF AGING | KENVUE BRANDS LLC | 2009-11-26 | — | — | US | disclosed |
| US-20090292027-A1 | COMPOSITIONS FOR THE TREATMENT OF SIGNS OF AGING | KENVUE BRANDS LLC | 2009-11-26 | — | — | US | disclosed |
| US-20090227683-A1 | Compositions for Providing an Analgesic Effect to the Skin | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. | 2009-09-10 | — | — | US | disclosed |
| US-20090227683-A1 | Compositions for Providing an Analgesic Effect to the Skin | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. | 2009-09-10 | — | — | US | disclosed |
| EP-2045297-A2 | Compositions for use in darkening skin | Johnson and Johnson Consumer Companies, Inc. (US) | 2009-04-08 | — | — | EP | disclosed |
| US-20090087395-A1 | COMPOSITIONS FOR USE IN DARKENING THE SKIN | JOHNSON & JOHNSON CONSUMER CO., INC. | 2009-04-02 | — | — | US | disclosed |
| US-20090087395-A1 | COMPOSITIONS FOR USE IN DARKENING THE SKIN | JOHNSON & JOHNSON CONSUMER CO., INC. | 2009-04-02 | — | — | US | disclosed |
| US-20070042010-A1 | Compositions containing amines and use thereof to treat acne or reduce the appearance of oil or pores on the skin | JOHNSON & JOHNSON CONSUMER INC. | 2007-02-22 | — | — | US | disclosed |
| US-20070042010-A1 | Compositions containing amines and use thereof to treat acne or reduce the appearance of oil or pores on the skin | JOHNSON & JOHNSON CONSUMER INC. | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120276226-A1 | COMPOSITIONS COMPRISING EXTRACTS OF SOUTHERNWOOD AND AN AMINE COMPOUND | CUTA, TYR, C5 | KDM4E 723/4885TSHR 4736/4885RECQL 3228/4885 |
| US-20090227683-A1 | Compositions for Providing an Analgesic Effect to the Skin | TRPA1, HRH2, HRH1 | KDM4E 3289/4885TSHR 2616/4885RECQL 572/4885 |
| US-20070042010-A1 | Compositions containing amines and use thereof to treat acne or reduce the appearance of oil or pores on the skin | CUTA, C3AR1, HCAR3 | KDM4E 3780/4885TSHR 1254/4885RECQL 1149/4885 |
| US-20090087395-A1 | COMPOSITIONS FOR USE IN DARKENING THE SKIN | TYR, CUTA, MC1R | KDM4E 1741/4885TSHR 3271/4885RECQL 548/4885 |
| US-20090292027-A1 | COMPOSITIONS FOR THE TREATMENT OF SIGNS OF AGING | CUTA, GLA, H1-3 | KDM4E 1661/4885TSHR 2546/4885RECQL 232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.