Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | JMJD6 | Q6NYC1 | 3/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6858064 | 0.92 | TBXAS1 (0.39) | TBXAS1KMT2AADORA3HSD17B10LMNA | |
| SCHEMBL6849821 | 0.92 | LMNA (0.40) | TBXAS1KMT2AADORA3JMJD6ADORA2A | |
| SCHEMBL6853830 | 0.87 | NOTUM (0.39) | KMT2AJMJD6MAPTKDM4EALDH1A1 | |
| SCHEMBL22040159 | 0.81 | JMJD6 (0.45) | KMT2AADORA3JMJD6ADORA2AADORA1 | |
| SCHEMBL6854963 | 0.80 | NOTUM (0.40) | KMT2AADORA2AKDM4EALDH1A1HPGD | |
| SCHEMBL6855523 | 0.80 | TSHR (0.39) | KDM4EALDH1A1HPGDHSD17B10NOTUM | |
| SCHEMBL6855286 | 0.79 | KMT2A (0.40) | KMT2AADORA3JMJD6ADORA2AADORA1 | |
| SCHEMBL4670651 | 0.77 | KMT2A (0.39) | KMT2AADORA3JMJD6ADORA2AADORA1 | |
| SCHEMBL24842047 | 0.76 | ADRB3 (0.40) | KMT2AMAPTALDH1A1NOTUM | |
| SCHEMBL29446057 | 0.76 | ALDH1A1 (0.36) | TBXAS1KMT2AADORA3JMJD6ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6831177-B1 | Preparation of their intermediates, 2-acyl-5-benzylfuran derivatives and 1,2,4-triazole-3- carboxylic acid ester derivatives | SHIONOGI & CO., LTD. (JP) | 2004-12-14 | — | — | US | disclosed |
| EP-1186599-A1 | NOVEL PROCESSES FOR THE PREPARATION OF SUBSTITUTED PROPENONE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 2002-03-13 | — | — | EP | disclosed |