SCHEMBL685626

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL685917	0.98	TRPA1 (0.58)	TRPA1SMPD1ALDH1A1MEN1KMT2A
	SCHEMBL28388362	0.89	TRPA1 (0.62)	TRPA1SMPD1ALDH1A1MEN1KMT2A
	SCHEMBL3761372	0.86	ALDH1A1 (0.43)	TRPA1SMPD1ALDH1A1CNR2PRKCE
	SCHEMBL11503669	0.85	ALDH1A1 (0.69)	SMPD1ALDH1A1MEN1KMT2ASTK17B
	SCHEMBL14856076	0.85	ALDH1A1 (0.69)	SMPD1ALDH1A1MEN1KMT2ASTK17B
	SCHEMBL31500474	0.84	TYR (0.58)	SMPD1ALDH1A1MEN1KMT2AAPP
	SCHEMBL1967921	0.83	TLR8 (0.40)	TRPA1ALDH1A1MEN1KMT2AAPP
	SCHEMBL15899460	0.83	TLR8 (0.40)	TRPA1ALDH1A1MEN1KMT2AAPP
	SCHEMBL15899585	0.83	TLR8 (0.40)	TRPA1ALDH1A1MEN1KMT2AAPP
	SCHEMBL14323012	0.83	ALDH1A1 (0.71)	SMPD1ALDH1A1MEN1KMT2ASTK17B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.