Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.43 |
| ▸ | AURKA | O14965 | 2/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSPO | P30536 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6856235 | 0.87 | AVPR1B (0.39) | LMNAKDM4EDHODHTSPO | |
| SCHEMBL6857165 | 0.85 | KDM4E (0.51) | LMNASMN1; SMN2AURKAAURKBKDM4E | |
| SCHEMBL6856769 | 0.81 | KMO (0.39) | PTGDR2KDM4EDHODHTSPOKMO | |
| SCHEMBL6855979 | 0.75 | AVPR1B (0.39) | LMNAKDM4EDHODHTSPO | |
| SCHEMBL6857065 | 0.73 | AVPR1B (0.45) | — | |
| SCHEMBL6857381 | 0.73 | MDM2 (0.40) | MDM2 | |
| SCHEMBL6857432 | 0.71 | AVPR1B (0.43) | SMN1; SMN2 | |
| SCHEMBL6856809 | 0.71 | MTNR1A (0.36) | AURKBTSPOKMOCASP3 | |
| SCHEMBL6857380 | 0.71 | TRPV1 (0.38) | KDM4E | |
| SCHEMBL12955882 | 0.70 | KDM4E (0.54) | LMNASMN1; SMN2PTGDR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011096461-A1 | QUINOLINE DERIVATIVE | 大正製薬株式会社 (JP) | 2011-08-11 | — | — | WO | disclosed |