Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.32 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | RXRB | P28702 | 1/20 | 0.30 |
| ▸ | RXRG | P48443 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5087199 | 0.73 | HSD11B1 (0.34) | DRD2MRGPRX1HSD11B1ADRA2AADRA2B | |
| SCHEMBL30093322 | 0.63 | CA1 (0.55) | ARADRA2B | |
| SCHEMBL255270 | 0.63 | CA1 (0.55) | ARADRA2B | |
| SCHEMBL1051260 | 0.62 | ADRA2A (0.42) | MRGPRX1HSD11B1ADRA2AADRA2BADRA2C | |
| SCHEMBL1685381 | 0.62 | LTA4H (0.46) | MRGPRX1HSD11B1ADRA2AADRA2BADRA2C | |
| SCHEMBL5083556 | 0.62 | HSD11B1 (0.34) | DRD2MRGPRX1HSD11B1ADRA2AADRA2B | |
| SCHEMBL13020168 | 0.61 | HSD11B1 (0.42) | MRGPRX1HSD11B1ADRA2AADRA2BADRA2C | |
| SCHEMBL10902334 | 0.61 | AR (0.53) | MRGPRX1HSD11B1ARADRA2AADRA2B | |
| SCHEMBL11048002 | 0.60 | LTA4H (0.45) | MRGPRX1HSD11B1ARADRA2AADRA2B | |
| SCHEMBL9242571 | 0.60 | HSD11B1 (0.53) | HSD11B1ADRA2AADRA2BADRA2CRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6787616-B2 | HIGH BULK DENSITY, NARROW PARTICLE SIZE AND MOLECULAR WEIGHT DISTRIBUTION, REDUCED FINES AND LARGE PARTICLE CONTENT; HIGH ACTIVITY | MARUZEN PETROCHEMICAL CO., LTD. (JP) | 2004-09-07 | — | — | US | disclosed |
| US-20040010104-A1 | Catalyst for olefin polymerization and process for polymerizing olefin by means thereof | MARUZEN PETROCHEMICAL CO., LTD. (JP) | 2004-01-15 | — | — | US | disclosed |