Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | QPCT | Q16769 | 1/20 | 0.30 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1116268 | 0.72 | ALDH1A1 (0.43) | PLAUFAAHCES1QPCTQPCTL | |
| SCHEMBL1116224 | 0.63 | HTR2A (0.41) | PLAUFAAHCES1QPCTQPCTL | |
| SCHEMBL1116221 | 0.63 | HTR2A (0.41) | PLAUFAAHCES1QPCTQPCTL | |
| SCHEMBL6858213 | 0.62 | GSK3B (0.39) | FAAHCES1QPCTQPCTL | |
| SCHEMBL30961329 | 0.60 | FAAH (0.46) | PLAUFAAHCES1GABRG2GABRB3 | |
| SCHEMBL14514377 | 0.60 | GABRG2 (0.45) | PLAUFAAHCES1GABRG2GABRB3 | |
| SCHEMBL29225233 | 0.58 | FAAH (0.45) | FAAHCES1QPCTQPCTL | |
| SCHEMBL30463591 | 0.58 | FAAH (0.45) | FAAHCES1QPCTQPCTL | |
| SCHEMBL3564079 | 0.57 | QPCT (0.53) | PLAUFAAHCES1QPCTQPCTL | |
| SCHEMBL16768951 | 0.57 | QPCT (0.39) | PLAUQPCTQPCTL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2281824-A1 | Furan-imidazolone derivatives, for the treatment of cognitive, neurodegenerative or neuronal diseases or disorders | NOSCIRA, S.A. (ES) | 2011-02-09 | — | — | EP | disclosed |