Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27649844 | 0.83 | PGR (0.34) | CA2ALDH1A1TSHRTDP1 | |
| SCHEMBL6220544 | 0.77 | POLB (0.38) | CA2ALDH1A1TSHRTDP1GRIN2D | |
| SCHEMBL23004 | 0.74 | CA2 (0.41) | CA2ALDH1A1TSHRTDP1GABRA1 | |
| SCHEMBL125906 | 0.74 | CA2 (0.41) | CA2ALDH1A1TSHRTDP1GABRA1 | |
| SCHEMBL2723894 | 0.74 | CA2 (0.37) | CA2ALDH1A1TSHRTDP1GABRA1 | |
| SCHEMBL4634623 | 0.74 | CA2 (0.37) | CA2ALDH1A1TSHRTDP1GABRA1 | |
| SCHEMBL4057050 | 0.73 | CA2 (0.50) | CA2ALDH1A1TSHRTDP1GABRA1 | |
| SCHEMBL10927467 | 0.73 | CA2 (0.39) | CA2ALDH1A1TSHRTDP1GABRA1 | |
| SCHEMBL24092 | 0.73 | CA2 (0.39) | CA2ALDH1A1TSHRTDP1GABRA1 | |
| SCHEMBL22639 | 0.73 | CA2 (0.39) | CA2ALDH1A1TSHRTDP1GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1110963-B1 | Chlorin- and bacteriochlorin-aminophenylDTPA conjugates for MR contrast media and radiopharmaceuticals | HEALTH RESEARCH INC (US) | 2004-04-21 | — | — | EP | claimed |
| US-6534040-B2 | Chlorin and bacteriochlorin-based aminophenyl DTPA and N2S2 conjugates for MR contrast media and radiopharmaceuticals | HEALTH RESEARCH, INC. | 2003-03-18 | — | — | US | claimed |
| US-20010046983-A1 | Chlorin and bacteriochlorin-based aminophenyl DTPA and N2S2 conjugates for MR contrast media and radiopharmaceuticals | HEALTH RESEARCH, INC. | 2001-11-29 | — | — | US | claimed |
| EP-1110963-A2 | Chlorin and bacteriochlorin-based aminophenyl DTPA and N2S2 conjugates for MR contrast media and radiopharmaceuticals | HEALTH RESEARCH, INC. (US) | 2001-06-27 | — | — | EP | claimed |
| EP-2699572-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | Origenis GmbH (DE) | 2014-02-26 | — | — | EP | disclosed |
| WO-2012143143-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | ORIGENIS GMBH (DE) | 2012-10-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010046983-A1 | Chlorin and bacteriochlorin-based aminophenyl DTPA and N2S2 conjugates for MR contrast media and radiopharmaceuticals | C1S, IWS1, CTPS2 | CA2 286/4885ALDH1A1 4844/4885TSHR 113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.