Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | MPL | P40238 | 2/20 | 0.32 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6858865 | 0.77 | CA2 (0.39) | ALDH1A1TDP1TSHRGRIN2DGRIN3B | |
| SCHEMBL81363 | 0.74 | ALDH1A1 (0.39) | POLBALDH1A1TDP1L3MBTL1GAA | |
| SCHEMBL82438 | 0.74 | TDP1 (0.34) | POLBALDH1A1TDP1L3MBTL1GAA | |
| SCHEMBL27649844 | 0.74 | PGR (0.34) | ALDH1A1TDP1TSHRCA2 | |
| SCHEMBL3338590 | 0.73 | CA2 (0.35) | POLBALDH1A1TDP1L3MBTL1TSHR | |
| SCHEMBL1068717 | 0.73 | CA2 (0.34) | POLBALDH1A1TDP1L3MBTL1GAA | |
| SCHEMBL10924037 | 0.73 | ALDH1A1 (0.33) | POLBALDH1A1TDP1L3MBTL1GAA | |
| SCHEMBL160262 | 0.73 | P2RX7 (0.36) | POLBALDH1A1TDP1L3MBTL1GAA | |
| SCHEMBL6591151 | 0.73 | NFKB1 (0.33) | POLBALDH1A1TDP1L3MBTL1GAA | |
| SCHEMBL330164 | 0.73 | HSD11B1 (0.37) | POLBALDH1A1TDP1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116745289-A | Agonists of free fatty acid receptor 1 and their use in diseases associated with said receptor | 奥洛治疗有限公司 | 2023-09-12 | — | — | CN | disclosed |
| EP-2897947-B1 | ALKYL, FLUOROALKYL-1,4-BENZODIAZEPINONE COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2016-10-26 | — | — | EP | disclosed |
| US-9242941-B2 | Alkyl, fluoroalkyl-1,4-benzodiazepinone compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-01-26 | — | — | US | disclosed |
| US-20150239851-A1 | ALKYL, FLUOROALKYL-1,4-BENZODIAZEPINONE COMPOUNDS | BRISTOL-METERS SQUIBB COMPANY (US) | 2015-08-27 | — | — | US | disclosed |
| CN-102438990-B | Substituted 2-acetamido-5-aryl-1, 2, 4-triazolones and use thereof | BAYER SCHERING PHARMA AG | 2014-08-20 | — | — | CN | disclosed |
| CN-103864704-A | Substituted 2-acetamido-5-aryl-1,2,4-triazolones and use thereof | BAYER SCHERING PHARMA AG | 2014-06-18 | — | — | CN | disclosed |
| CN-103097355-A | Novel quinoline esters useful for treating skin disorders | WYETH LLC | 2013-05-08 | — | — | CN | disclosed |
| CN-102056907-A | Heterocyclic derivative and use thereof | TAKEDA PHARMACEUTICAL | 2011-05-11 | — | — | CN | disclosed |
| CN-101679311-A | Quinazoline compound | WYETH CORP | 2010-03-24 | — | — | CN | disclosed |
| CN-101541751-A | Quinoline compounds | WYETH CORP (US) | 2009-09-23 | — | — | CN | disclosed |
| CN-1914173-A | Quinolines useful in treating cardiovascular disease | WYETH CORP (US) | 2007-02-14 | — | — | CN | disclosed |
| US-6878663-B2 | Method for producing palladium complex compound | CENTRAL GLASS COMPANY, LIMITED (JP) | 2005-04-12 | — | — | US | disclosed |
| EP-1008601-B1 | Method for producing palladium complex compound | CENTRAL GLASS CO LTD (JP) | 2005-03-09 | — | — | EP | disclosed |
| US-6706905-B1 | REACTING AROMATIC COMPOUND, PALLADIUM(II) COMPOUND, AND PHOSPHINE DERIVATIVE; COMPLEXING WITH BENZOIC ACID DERIVATIVE; METALLIZATION | CENTRAL GLASS COMPANY, LIMITED (JP) | 2004-03-16 | — | — | US | disclosed |
| US-20020111482-A1 | Method for producing palladium complex compound | CENTRAL GLASS COMPANY, LIMITED | 2002-08-15 | — | — | US | disclosed |
| EP-1008601-A2 | Method for producing palladium complex compound | Central Glass Company, Limited (JP) | 2000-06-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020111482-A1 | Method for producing palladium complex compound | PDCD1LG2, CD274, PDCD1 | POLB 925/4885ALDH1A1 278/4885TDP1 2018/4885 |
| US-20150239851-A1 | ALKYL, FLUOROALKYL-1,4-BENZODIAZEPINONE COMPOUNDS | CNR1, CNR2, NR1I3 | POLB 4589/4885ALDH1A1 902/4885TDP1 2575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.