SCHEMBL6860111

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6870356	0.86	GABRA2 (0.34)	GABRA2GABRB2
	SCHEMBL2831553	0.77	MAPT (0.40)	GABRA2GABRB2MAPTHPGDNPSR1
	SCHEMBL6959168	0.72	GABRA2 (0.45)	GABRA2GABRB2MAPT
	SCHEMBL6867220	0.72	MAPT (0.47)	GABRA2GABRB2MAPTHPGDNPSR1
	SCHEMBL6869652	0.72	ALDH1A1 (0.53)	MAPTHPGDNPSR1ALDH1A1KDM4E
	SCHEMBL3200271	0.72	MAPT (0.38)	GABRA2GABRB2MAPTHPGDNPSR1
	SCHEMBL7238315	0.72	MAPT (0.43)	GABRA2GABRB2MAPTHPGDNPSR1
	SCHEMBL2829188	0.71	MAPT (0.42)	GABRA2GABRB2MAPTHPGDNPSR1
	SCHEMBL7101511	0.71	GABRA2 (0.43)	GABRA2GABRB2
	SCHEMBL3219619	0.71	MAPT (0.40)	GABRA2GABRB2MAPTHPGDNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.