Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 5/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6860111 | 0.86 | GABRA2 (0.36) | GABRA2GABRB2 | |
| SCHEMBL6864489 | 0.78 | GABRA2 (0.37) | GABRA2GABRB2 | |
| SCHEMBL6865680 | 0.73 | CYP1A2 (0.36) | GABRA2GABRB2 | |
| SCHEMBL7101511 | 0.69 | GABRA2 (0.43) | GABRA2GABRB2 | |
| SCHEMBL7095243 | 0.68 | GABRA2 (0.43) | GABRA2GABRB2 | |
| SCHEMBL6976748 | 0.68 | GABRA2 (0.43) | GABRA2GABRB2 | |
| SCHEMBL7094294 | 0.68 | GABRA2 (0.42) | GABRA2GABRB2 | |
| SCHEMBL6865360 | 0.68 | GABRB3 (0.36) | GABRA2GABRB2 | |
| SCHEMBL6969574 | 0.68 | GABRA2 (0.43) | GABRA2GABRB2 | |
| SCHEMBL7097797 | 0.68 | GABRA2 (0.42) | GABRA2GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030130307-A1 | Heterocycles | BANKS BERNARD JOSEPH (GB) | 2003-07-10 | — | — | US | claimed |
| US-20010005725-A1 | Heterocycles | BANKS BERNARD JOSEPH (GB) | 2001-06-28 | — | — | US | claimed |
| EP-0957094-A1 | 1-(2-Halogenaryl)azoles as antiparasitic agents | PFIZER INC. (US) | 1999-11-17 | — | — | EP | claimed |
| US-6812241-B2 | FOR PLANTS, HUMANS, VETERINARY MEDICINE | PFIZER INC. | 2004-11-02 | — | — | US | disclosed |
| US-20030130307-A1 | Heterocycles | BANKS BERNARD JOSEPH (GB) | 2003-07-10 | — | — | US | disclosed |
| US-6525079-B2 | Antiparasitic compounds such as 4-(2,2-dibromocyclopropyl)-1-(2,6-dichloro-4-trifluoromethylphenyl)-1,2,3 -triazole | PFIZER INC. | 2003-02-25 | — | — | US | disclosed |
| US-20010005725-A1 | Heterocycles | BANKS BERNARD JOSEPH (GB) | 2001-06-28 | — | — | US | disclosed |
| US-6110958-A | PARASITICIDES | PFIZER INC. (US) | 2000-08-29 | — | — | US | disclosed |
| US-6083965-A | ANTIPARASITIC AGENTS | PFIZER INC (US) | 2000-07-04 | — | — | US | disclosed |
| EP-0957094-A1 | 1-(2-Halogenaryl)azoles as antiparasitic agents | PFIZER INC. (US) | 1999-11-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130307-A1 | Heterocycles | CYP1A1, CYP2E1, CYP1B1 | GABRA2 2526/4885GABRB2 1986/4885KCNH2 907/4885 |
| US-20010005725-A1 | Heterocycles | CYP1A1, CYP2E1, CYP1B1 | GABRA2 2526/4885GABRB2 1986/4885KCNH2 907/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.