Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6866204 | 0.91 | FFAR1 (0.38) | TSHRHDAC3HDAC1FFAR1KDM4E | |
| SCHEMBL6866219 | 0.90 | RXFP1 (0.43) | TSHRHDAC3HDAC1CA12CA9 | |
| SCHEMBL6864851 | 0.88 | HDAC3 (0.38) | TSHRHDAC3HDAC1CA12CA9 | |
| SCHEMBL7048492 | 0.82 | PTGES (0.50) | EPHX2 | |
| SCHEMBL6864874 | 0.81 | RXFP1 (0.37) | HDAC3HDAC1FFAR1ALDH1A1KMT2A | |
| SCHEMBL7051034 | 0.81 | PTGES (0.49) | CETPEPHX2 | |
| SCHEMBL6860325 | 0.80 | SLC16A3 (0.42) | HDAC3HDAC1FFAR1KDM4ELMNA | |
| SCHEMBL6864455 | 0.79 | ACACB (0.38) | GAAHDAC3HDAC1FFAR1KDM4E | |
| SCHEMBL6860157 | 0.78 | CA2 (0.53) | CA12CA9KMT2A | |
| SCHEMBL7080234 | 0.77 | MMP2 (0.43) | TSHRHDAC3HDAC1FFAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6812252-B2 | ACYLSULFONAMIDE DERIVATIVES CONTAINING FLUOROSUBSTITUTEDPHENYLETHYNYL GROUP HAVING A HYPOGLYCEMIC EFFECT AND FREE OF THE SIDE EFFECT | AJINOMOTO CO., INC. (JP) | 2004-11-02 | — | — | US | disclosed |
| US-20030191323-A1 | Hypoglycemic agent | AJINOMOTO CO., INC. (JP) | 2003-10-09 | — | — | US | disclosed |
| US-20030181764-A1 | Acylsulfonamide derivatives | AJINOMOTO CO. INC (JP) | 2003-09-25 | — | — | US | disclosed |
| EP-1316548-A1 | ACYLSULFONAMIDE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2003-06-04 | — | — | EP | disclosed |
| EP-1300142-A1 | HYPOGLYCEMICS | Ajinomoto Co., Inc. (JP) | 2003-04-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030181764-A1 | Acylsulfonamide derivatives | DPP4, SLC5A2, GLP1R | TSHR 1566/4885GAA 130/4885HDAC3 33/4885 |
| US-20030191323-A1 | Hypoglycemic agent | GPR119, IAPP, SLC5A2 | TSHR 3150/4885GAA 40/4885HDAC3 207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.