Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 8/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 5/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6860844 | 0.84 | CYP2C19 (0.43) | SMN1; SMN2MAPTPOLBLMNAMEN1 | |
| SCHEMBL6860475 | 0.83 | LMNA (0.44) | SMN1; SMN2MAPTPOLBLMNAMEN1 | |
| SCHEMBL6861342 | 0.82 | GRIA2 (0.54) | MAPTPOLBLMNATSHRGAA | |
| SCHEMBL6861147 | 0.79 | ABHD6 (0.48) | SMN1; SMN2MAPTPOLBLMNAMEN1 | |
| SCHEMBL6864318 | 0.75 | KDM4E (0.44) | SMN1; SMN2MAPTPOLBLMNAMEN1 | |
| SCHEMBL6861702 | 0.75 | MAPT (0.43) | SMN1; SMN2MAPTPOLBLMNAMEN1 | |
| SCHEMBL6861498 | 0.73 | GRIA2 (0.44) | MAPTPOLBLMNATP53CYP2C19 | |
| SCHEMBL15491619 | 0.69 | LMNA (0.48) | SMN1; SMN2MAPTLMNATSHRGAA | |
| SCHEMBL6861919 | 0.68 | MAPT (0.52) | SMN1; SMN2MAPTPOLBLMNAMEN1 | |
| SCHEMBL6862518 | 0.68 | TP53 (0.76) | SMN1; SMN2MAPTPOLBLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011036889-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2011-03-31 | — | — | WO | disclosed |