Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 2/20 | 0.33 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6600450 | 0.68 | NOS3 (0.35) | NPSR1ALDH1A1TP53MAPTRAB9A | |
| SCHEMBL6864671 | 0.67 | CYP2A13 (0.33) | ALDH1A1LMNACYP2A13RAB9AKMT2A | |
| SCHEMBL6602644 | 0.66 | NPSR1 (0.38) | NPSR1ALDH1A1TP53POLBHSD11B1 | |
| SCHEMBL31323968 | 0.65 | ALDH1A1 (0.38) | HTTALDH1A1LMNAPOLBMAPT | |
| SCHEMBL394140 | 0.63 | MAPT (0.38) | HTTNPSR1ALDH1A1LMNAMAPT | |
| SCHEMBL692241 | 0.63 | HSP90AA1 (0.40) | HTTNPSR1ALDH1A1 | |
| SCHEMBL8028523 | 0.63 | NPC1 (0.34) | ALDH1A1RAB9A | |
| SCHEMBL7808814 | 0.63 | TP53 (0.40) | ALDH1A1TP53MAPTMEN1KMT2A | |
| SCHEMBL6861158 | 0.62 | DGAT1 (0.35) | ALDH1A1LMNAMAPTGAAMEN1 | |
| SCHEMBL270530 | 0.62 | SIGMAR1 (0.67) | KCNH2ALDH1A1SIGMAR1LMNATEAD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0797574-B1 | 1,3,4-OXADIAZINE DERIVATIVES HAVING A PESTICIDE EFFECT | BAYER CROPSCIENCE AG (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-5883091-A | 1,3,4-oxadiazine derivatives having a pesticide effect | BAYER AKTIENGESELLSCHAFT (DE) | 1999-03-16 | — | — | US | disclosed |
| EP-0797574-A1 | 1,3,4-OXADIAZINE DERIVATIVES HAVING A PESTICIDE EFFECT | BAYER AG (DE) | 1997-10-01 | — | — | EP | disclosed |
| WO-1996018624-A1 | 1,3,4-OXADIAZINE DERIVATIVES HAVING A PESTICIDE EFFECT | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-20 | — | — | WO | disclosed |