Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CXCR3 | P49682 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RHOC | P08134 | 3/20 | 0.38 |
| ▸ | RHOA | P61586 | 3/20 | 0.38 |
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6863510 | 0.92 | EPHX2 (0.45) | EPHX2LMNACXCR3GAARHOC | |
| SCHEMBL6863997 | 0.86 | EPHX2 (0.47) | EPHX2CXCR3GAARHOCRHOA | |
| SCHEMBL12014289 | 0.85 | MGLL (0.46) | EPHX2CXCR3GAARHOCRHOA | |
| SCHEMBL6863250 | 0.84 | EPHX2 (0.62) | EPHX2CXCR3 | |
| SCHEMBL12005298 | 0.82 | S1PR2 (0.44) | EPHX2LMNAKMT2ATHRBACP1 | |
| SCHEMBL12015274 | 0.82 | LMNA (0.40) | EPHX2LMNAKMT2AACP1 | |
| SCHEMBL6862582 | 0.81 | CXCR3 (0.47) | EPHX2LMNACXCR3KMT2ATHRB | |
| SCHEMBL26634671 | 0.79 | LMNA (0.60) | LMNAGAAKMT2ATHRBTP53 | |
| SCHEMBL4279051 | 0.78 | CXCR3 (0.44) | EPHX2LMNACXCR3GAARHOC | |
| SCHEMBL4274878 | 0.77 | CXCR3 (0.45) | EPHX2LMNACXCR3GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011032291-A1 | SELECTIVE CALCIUM CHANNEL MODULATORS | ZALICUS PHARMACEUTICALS LTD . (CA) | 2011-03-24 | — | — | WO | disclosed |