Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.40 |
| ▸ | RHOC | P08134 | 1/20 | 0.40 |
| ▸ | RHOA | P61586 | 1/20 | 0.40 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6862660 | 0.91 | CXCR3 (0.48) | CXCR3LMNAALDH1A1CACNA1HEPHX2 | |
| SCHEMBL6863165 | 0.87 | CXCR3 (0.47) | CXCR3LMNAALDH1A1CACNA1HEPHX2 | |
| SCHEMBL12014293 | 0.83 | CXCR3 (0.46) | CXCR3CACNA1HEPHX2RHOCRHOA | |
| SCHEMBL6863055 | 0.82 | CACNA1H (0.52) | CXCR3LMNAALDH1A1CACNA1HTHRB | |
| SCHEMBL6862576 | 0.81 | EPHX2 (0.44) | CXCR3LMNAKMT2AEPHX2THRB | |
| SCHEMBL4277997 | 0.78 | CXCR3 (0.55) | CXCR3LMNAALDH1A1EPHX2KCNH2 | |
| SCHEMBL26634671 | 0.76 | LMNA (0.60) | LMNAKMT2AALDH1A1THRBRAB9A | |
| SCHEMBL4278127 | 0.74 | CXCR3 (0.56) | CXCR3LMNAALDH1A1EPHX2KCNH2 | |
| SCHEMBL12004810 | 0.74 | CXCR3 (0.53) | CXCR3LMNAALDH1A1EPHX2KCNH2 | |
| SCHEMBL1445327 | 0.73 | LMNA (0.52) | CXCR3LMNAALDH1A1EPHX2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011032291-A1 | SELECTIVE CALCIUM CHANNEL MODULATORS | ZALICUS PHARMACEUTICALS LTD . (CA) | 2011-03-24 | — | — | WO | disclosed |