Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALPI | P09923 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALPG | P10696 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7653658 | 0.79 | KDM4E (0.44) | KDM4EALDH1A1POLBGAAL3MBTL1 | |
| SCHEMBL6864033 | 0.78 | GAA (0.47) | RAB9AALDH1A1LMNAGAAMAPT | |
| SCHEMBL4609315 | 0.77 | TAS1R3 (0.38) | KDM4ETAS1R3TAS1R1NPC1RAB9A | |
| SCHEMBL8501576 | 0.75 | HPGD (0.50) | NPC1RAB9AALDH1A1LMNAGAA | |
| SCHEMBL15358753 | 0.73 | TAS1R3 (0.38) | KDM4ETAS1R3TAS1R1NPC1RAB9A | |
| SCHEMBL28453112 | 0.72 | FOLH1 (0.44) | TAS1R3TAS1R1PRKACACDK8GSK3A | |
| SCHEMBL19312017 | 0.71 | TAS1R3 (0.35) | KDM4ETAS1R3TAS1R1LMNAPOLB | |
| SCHEMBL28443884 | 0.71 | HDAC1 (0.46) | TAS1R3TAS1R1HDAC1 | |
| SCHEMBL11341058 | 0.71 | KDM4E (0.58) | KDM4ENSD2ALDH1A1LMNAALPL | |
| SCHEMBL4581666 | 0.71 | NTRK2 (0.56) | KDM4EALDH1A1POLBMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131280-B1 | PREPARATION OF 5-AMINO-ISOPHTHALAMIDES | AMERSHAM HEALTH AS (NO) | 2004-08-11 | — | — | EP | disclosed |
| US-6441235-B1 | DI-LOWER-ALKYL-5-NITROISOPHTHALATE REACTS WITH A DIHYDROXY-MONOALKYLAMINE IN THE PRESENCE OF A BASIC CATALYST AND THEN CATALYLYTICALLY HYDROGENATED, WITHOUT ISOLATING THE 5-NITRO-N,N'-BIS(R)ISOPHTHALAMIDE INTERMEDIATE | AMERSHA, HEALTH AS (NO) | 2002-08-27 | — | — | US | disclosed |
| US-20020095053-A1 | Preparation of 5-amino-isophthalamides | GE HEALTHCARE AS (NO) | 2002-07-18 | — | — | US | disclosed |
| EP-1131280-A1 | PREPARATION OF 5-AMINO-ISOPHTHALAMIDES | Amersham Health AS (NO) | 2001-09-12 | — | — | EP | disclosed |
| WO-2000029372-A1 | PREPARATION OF 5-AMINO-ISOPHTHALAMIDES | NYCOMED IMAGING AS (NO) | 2000-05-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020095053-A1 | Preparation of 5-amino-isophthalamides | DNPH1, DDAH1, DOHH | KDM4E 3057/4885TAS1R3 3554/4885TAS1R1 4033/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.