Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 17/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6863092 | 0.89 | ADORA2A (0.64) | ADORA2AMEN1KMT2A | |
| SCHEMBL6871448 | 0.89 | ADORA2A (0.65) | ADORA2A | |
| SCHEMBL6869733 | 0.87 | ADORA2A (0.52) | ADORA2A | |
| SCHEMBL6863385 | 0.82 | MEN1 (0.47) | ADORA2AMEN1KMT2ACA2 | |
| SCHEMBL6869803 | 0.81 | ADORA2A (0.41) | ADORA2AMEN1KMT2ACA2 | |
| SCHEMBL6871404 | 0.81 | ADORA2A (0.51) | ADORA2A | |
| SCHEMBL6872923 | 0.81 | ADORA2A (0.46) | ADORA2AKMT2A | |
| SCHEMBL6869836 | 0.81 | ADORA2A (0.61) | ADORA2A | |
| SCHEMBL6869707 | 0.79 | KIT (0.44) | ADORA2AMEN1KMT2ACA2 | |
| SCHEMBL6863068 | 0.79 | ADORA2A (0.61) | ADORA2AMEN1KMT2ACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347974-B1 | AMINOTRIAZOLOPYRIDIINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 2004-11-03 | — | — | EP | disclosed |
| US-6506772-B1 | Pharmaceutically active salts thereof with activity as adenosine receptor ligands are disclosed. These compounds are the adenosine receptor. | HOFFMANN-LA ROCHE INC. | 2003-01-14 | — | — | US | disclosed |