Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 8/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6863385 | 0.86 | MEN1 (0.47) | ADORA2AMEN1KMT2ACA2POLB | |
| SCHEMBL6869838 | 0.85 | ADORA2A (0.43) | ADORA2AMEN1KMT2APOLB | |
| SCHEMBL6871448 | 0.81 | ADORA2A (0.65) | ADORA2ATDP1 | |
| SCHEMBL6863092 | 0.81 | ADORA2A (0.64) | ADORA2AMEN1KMT2A | |
| SCHEMBL6863733 | 0.81 | ADORA2A (0.50) | ADORA2AMEN1KMT2ACA2 | |
| SCHEMBL6869746 | 0.80 | PLAU (0.43) | ADORA2AMEN1KMT2APOLB | |
| SCHEMBL6870530 | 0.80 | ADORA2A (0.43) | ADORA2AMEN1KMT2APOLBKDR | |
| SCHEMBL6869707 | 0.79 | KIT (0.44) | ADORA2AMEN1KMT2ACA2POLB | |
| SCHEMBL6863068 | 0.79 | ADORA2A (0.61) | ADORA2AMEN1KMT2ACA2POLB | |
| SCHEMBL6871283 | 0.78 | PTGER2 (0.44) | ADORA2AMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347974-B1 | AMINOTRIAZOLOPYRIDIINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 2004-11-03 | — | — | EP | disclosed |