Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6870443 | 0.84 | LMNA (0.45) | ADORA2AMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL6868095 | 0.83 | KDM4E (0.53) | ADORA2AMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL6870459 | 0.82 | ADORA2A (0.43) | ADORA2ARAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL6871945 | 0.82 | ADORA2A (0.42) | ADORA2AMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL6869619 | 0.81 | MEN1 (0.44) | ADORA2AMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL6873063 | 0.81 | MEN1 (0.44) | ADORA2AMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL6868478 | 0.80 | ADORA2A (0.64) | ADORA2ARAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL7153750 | 0.79 | ADORA2A (0.71) | ADORA2AALDH1A1KDM4EHTT | |
| SCHEMBL6863751 | 0.79 | ADORA2A (0.62) | ADORA2AMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL6871217 | 0.79 | ADORA2A (0.98) | ADORA2AMEN1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347974-B1 | AMINOTRIAZOLOPYRIDIINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 2004-11-03 | — | — | EP | disclosed |