Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 4/20 | 0.47 |
| ▸ | CNR2 | P34972 | 3/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6869838 | 0.85 | ADORA2A (0.43) | KDM4EHTTMAPTALDH1A1ADORA2A | |
| SCHEMBL6868478 | 0.85 | ADORA2A (0.64) | KDM4EHTTALDH1A1ADORA2ASMN1; SMN2 | |
| SCHEMBL6867019 | 0.85 | DYRK1A (0.47) | KDM4EHTTALDH1A1ADORA2ASMN1; SMN2 | |
| SCHEMBL6863385 | 0.84 | MEN1 (0.47) | CNR1ADORA2ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL6863748 | 0.83 | ADORA2A (0.64) | KDM4EHTTMAPTALDH1A1ADORA2A | |
| SCHEMBL6868261 | 0.83 | NPC1 (0.48) | KDM4EHTTCNR1MAPTALDH1A1 | |
| SCHEMBL6870443 | 0.81 | LMNA (0.45) | KDM4EMAPTALDH1A1ADORA2ASMN1; SMN2 | |
| SCHEMBL6870751 | 0.81 | ADORA2A (0.41) | KDM4EHTTALDH1A1ADORA2ALMNA | |
| SCHEMBL6869733 | 0.81 | ADORA2A (0.52) | KDM4EHTTMAPTALDH1A1ADORA2A | |
| SCHEMBL6873039 | 0.81 | ADORA2A (0.66) | ALDH1A1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347974-B1 | AMINOTRIAZOLOPYRIDIINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 2004-11-03 | — | — | EP | disclosed |