Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | F12 | P00748 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6871382 | 0.86 | ADORA2A (0.59) | ADORA2ANPC1RAB9AF12HPGD | |
| SCHEMBL6868095 | 0.85 | KDM4E (0.53) | ADORA2AKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6863068 | 0.85 | ADORA2A (0.61) | ADORA2ASMN1; SMN2NPC1RAB9AKDR | |
| SCHEMBL6863074 | 0.80 | ADORA2A (0.62) | ADORA2AKDM4EALDH1A1SMN1; SMN2HTT | |
| SCHEMBL6868483 | 0.80 | ADORA2A (0.64) | ADORA2AKDRF12 | |
| SCHEMBL6863748 | 0.80 | ADORA2A (0.64) | ADORA2AKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6871945 | 0.80 | ADORA2A (0.42) | ADORA2AKDM4EALDH1A1LMNANPC1 | |
| SCHEMBL6867942 | 0.79 | ADORA2A (0.71) | ADORA2AKDM4EF12 | |
| SCHEMBL6869099 | 0.79 | ADORA2A (0.98) | ADORA2AF12HPGD | |
| SCHEMBL6871467 | 0.79 | ADORA2A (0.98) | ADORA2AF12HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347974-B1 | AMINOTRIAZOLOPYRIDIINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 2004-11-03 | — | — | EP | disclosed |