SCHEMBL6864487

SCHEMBL6864487

C=CCC[SiH2]c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
TSHR P16473 2/20 0.33
IDH1 O75874 1/20 0.33
ACHE P22303 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14956700 0.78 ALDH1A1 (0.37) ALDH1A1
SCHEMBL14956807 0.77 ALDH1A1 (0.33) ALDH1A1
SCHEMBL463323 0.76 ALDH1A1 (0.36) ALDH1A1TSHRCYP2C19
SCHEMBL14956609 0.74 KDM4E (0.35) ALDH1A1
SCHEMBL14957003 0.71 ALDH1A1 (0.38) ALDH1A1
SCHEMBL29926801 0.70 ALDH1A1 (0.32) ALDH1A1
SCHEMBL14956879 0.70 ALDH1A1 (0.34) ALDH1A1
SCHEMBL2272019 0.69 ALDH1A1 (0.31) ALDH1A1TSHR
SCHEMBL28598231 0.69 LOXL2 (0.32) ALDH1A1
SCHEMBL3682860 0.69 TP53 (0.38) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1204149-C Improved olefin polymerization process DOW CHEMICAL CO (US) 2005-06-01 CN disclosed
EP-1054910-B1 IMPROVED OLEFIN POLYMERIZATION PROCESS DOW GLOBAL TECHNOLOGIES INC (US) 2004-09-22 EP disclosed
US-6258902-B1 USING A METAL COMPLEX CATALYST AND AN ALKENYL CONTAINING HYDROCARBYLSILANE THE DOW CHEMICAL COMPANY 2001-07-10 US disclosed