SCHEMBL2272019

SCHEMBL2272019

ClCC[SiH2]c1ccccc1

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.31
MAPK1 P28482 2/20 0.31
TRPA1 O75762 1/20 0.31
GSK3B P49841 1/20 0.31
HIF1A Q16665 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL448266 0.78
SCHEMBL3684087 0.77 ALDH1A1 (0.46) ALDH1A1TSHR
SCHEMBL13169411 0.77 MAOB (0.41) ALDH1A1
SCHEMBL29926801 0.76 ALDH1A1 (0.32) ALDH1A1MAPK1
Hydrochloric Acid SCHEMBL28485238 0.76 ALDH1A1 (0.32) ALDH1A1MAPK1TRPA1GSK3BHIF1A
SCHEMBL7363535 0.74 TDP1 (0.40) ALDH1A1MAPK1TSHR
SCHEMBL3682860 0.74 TP53 (0.38) ALDH1A1MAPK1
SCHEMBL28598231 0.74 LOXL2 (0.32) ALDH1A1MAPK1
SCHEMBL13169407 0.72 MAOA (0.42) ALDH1A1
SCHEMBL23701116 0.70 TSHR (0.30) ALDH1A1MAPK1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103003367-B Curable resin composition and cured article DAICEL CORP. (JP) 2015-09-30 CN disclosed
CN-103154145-B Curable resin composition and cured article DAICEL CORP. (JP) 2015-09-16 CN disclosed
US-8871890-B2 Curable resin composition and cured article DAICEL CORPORATION (JP) 2014-10-28 US disclosed
EP-2636706-A1 CURABLE RESIN COMPOSITION AND CURED ARTICLE Daicel Corporation (JP) 2013-09-11 EP disclosed
CN-103154145-A Curable resin composition and cured article DAICEL CORP 2013-06-12 CN disclosed
US-20130131265-A1 CURABLE RESIN COMPOSITION AND CURED ARTICLE DAICEL CORPORATION (JP) 2013-05-23 US disclosed
CN-103003367-A Curable resin composition and cured product DAICEL CORP 2013-03-27 CN disclosed
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed