Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 11/20 | 0.40 |
| ▸ | BTK | Q06187 | 2/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | TEC | P42680 | 1/20 | 0.34 |
| ▸ | TXK | P42681 | 1/20 | 0.34 |
| ▸ | BMX | P51813 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13506119 | 0.92 | GPR52 (0.40) | GPR52RORCWNT3ATACR1P2RX7 | |
| SCHEMBL6865232 | 0.90 | GPR52 (0.48) | GPR52BTKTECTXKBMX | |
| SCHEMBL13506389 | 0.89 | PDE4B (0.46) | GPR52 | |
| SCHEMBL6864531 | 0.88 | PDE4B (0.37) | GPR52RORCWNT3ASCN9AP2RX7 | |
| SCHEMBL6864528 | 0.87 | GPR52 (0.55) | GPR52TACR1 | |
| SCHEMBL13505881 | 0.82 | GPR52 (0.49) | GPR52 | |
| SCHEMBL6864177 | 0.80 | GPR52 (0.51) | GPR52 | |
| SCHEMBL13506622 | 0.79 | LMNA (0.46) | RORCWNT3AP2RX7 | |
| SCHEMBL13506435 | 0.79 | PDE4B (0.48) | GPR52 | |
| SCHEMBL6863891 | 0.77 | GPR52 (0.64) | GPR52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2518054-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011078360-A1 | AMIDE COMPOUND | 武田薬品工業株式会社 (JP) | 2011-06-30 | — | — | WO | disclosed |