Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
| ▸ | WNT3A | P56704 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.33 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13506622 | 0.92 | LMNA (0.46) | PDE4BLMNAWNT3AMEN1KMT2A | |
| SCHEMBL13505588 | 0.89 | PDE4B (0.52) | PDE4BLMNAMEN1HPGDKMT2A | |
| SCHEMBL6865532 | 0.88 | GPR52 (0.40) | GPR52WNT3ARORCP2RX7SCN9A | |
| SCHEMBL13505604 | 0.86 | GPR52 (0.45) | GPR52WNT3ASMN1; SMN2 | |
| SCHEMBL6865232 | 0.81 | GPR52 (0.48) | GPR52SMN1; SMN2 | |
| SCHEMBL13506119 | 0.79 | GPR52 (0.40) | LMNAGPR52WNT3ASLC2A1RORC | |
| SCHEMBL13506492 | 0.79 | GPR52 (0.41) | PDE4BLMNAGPR52AURKARPS6KB1 | |
| SCHEMBL13506389 | 0.77 | PDE4B (0.46) | PDE4BLMNAGPR52MEN1HPGD | |
| SCHEMBL13506443 | 0.76 | GPR52 (0.42) | LMNAGPR52AURKARPS6KB1KMT2A | |
| SCHEMBL6864528 | 0.75 | GPR52 (0.55) | GPR52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2518054-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011078360-A1 | AMIDE COMPOUND | 武田薬品工業株式会社 (JP) | 2011-06-30 | — | — | WO | disclosed |