Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | EED | O75530 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FGB | P02675 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL687468 | 0.98 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2HPGDKMT2AMEN1 | |
| Lithium SCHEMBL686643 | 0.96 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2HPGDKMT2AMEN1 | |
| SCHEMBL688041 | 0.88 | EED (0.46) | SMN1; SMN2KMT2AMEN1MAPTRAB9A | |
| SCHEMBL687814 | 0.85 | EED (0.47) | SMN1; SMN2KMT2AMEN1MAPTRAB9A | |
| Lithium SCHEMBL688043 | 0.84 | EED (0.46) | SMN1; SMN2KMT2AMEN1MAPTRAB9A | |
| SCHEMBL6092486 | 0.80 | APAF1 (0.43) | ALDH1A1SMN1; SMN2HPGDGAAMAPT | |
| SCHEMBL30832650 | 0.80 | APAF1 (0.43) | ALDH1A1SMN1; SMN2HPGDGAAMAPT | |
| SCHEMBL6904573 | 0.78 | APAF1 (0.46) | ALDH1A1SMN1; SMN2HPGDGAAMAPT | |
| SCHEMBL8244044 | 0.77 | DRD2 (0.48) | KMT2AMAPTLMNAMAPK1EGFR | |
| SCHEMBL8796353 | 0.76 | MEN1 (0.49) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242471-B1 | SUBSTITUTED GROUP 4 METAL COMPLEXES, CATALYSTS AND OLEFIN POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-02-29 | — | — | EP | disclosed |
| CN-1495188-A | Substituted tetrels metal complex, catalyst and olefin polymerization method | — | 2004-05-12 | — | — | CN | disclosed |
| CN-1409729-A | Substituted group 4 metal complexes, catalysts and olefin polymerization processes | DOW GLOBAL TECHNOLOGY CO (US) | 2003-04-09 | — | — | CN | disclosed |
| US-6515155-B1 | Group 4 metal complexes of the constrained geometry type, catalysts derived therefrom and polymerization processes using the same, characterized by a nitrogen containing aliphatic or cycloaliphatic moiety that is substituted with one or more | DOW GLOBAL TECHNOLOGIES INC. | 2003-02-04 | — | — | US | disclosed |
| EP-1242471-A1 | SUBSTITUTED GROUP 4 METAL COMPLEXES, CATALYSTS AND OLEFIN POLYMERIZATION PROCESS | THE DOW CHEMICAL COMPANY (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001042315-A1 | SUBSTITUTED GROUP 4 METAL COMPLEXES, CATALYSTS AND OLEFIN POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2001-06-14 | — | — | WO | disclosed |