Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 8/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 8/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 8/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 8/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 8/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | FGB | P02675 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL687814 | 0.98 | EED (0.47) | EEDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL688041 | 0.97 | EED (0.46) | EEDGRIN2DGRIN3BGRIN1GRIN2A | |
| Lithium SCHEMBL686643 | 0.88 | ALDH1A1 (0.42) | EEDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL687468 | 0.86 | ALDH1A1 (0.44) | EEDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL686641 | 0.84 | ALDH1A1 (0.42) | EEDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6092486 | 0.77 | APAF1 (0.43) | MAPTKDM4EMAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL30832650 | 0.77 | APAF1 (0.43) | MAPTKDM4EMAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL6904573 | 0.75 | APAF1 (0.46) | MAPTLMNAMAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL8244044 | 0.74 | DRD2 (0.48) | KMT2AMAPTLMNAMAPK1HRH4 | |
| SCHEMBL1115534 | 0.73 | KMT2A (0.39) | EEDGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242471-B1 | SUBSTITUTED GROUP 4 METAL COMPLEXES, CATALYSTS AND OLEFIN POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-02-29 | — | — | EP | disclosed |
| US-6515155-B1 | Group 4 metal complexes of the constrained geometry type, catalysts derived therefrom and polymerization processes using the same, characterized by a nitrogen containing aliphatic or cycloaliphatic moiety that is substituted with one or more | DOW GLOBAL TECHNOLOGIES INC. | 2003-02-04 | — | — | US | disclosed |
| EP-1242471-A1 | SUBSTITUTED GROUP 4 METAL COMPLEXES, CATALYSTS AND OLEFIN POLYMERIZATION PROCESS | THE DOW CHEMICAL COMPANY (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001042315-A1 | SUBSTITUTED GROUP 4 METAL COMPLEXES, CATALYSTS AND OLEFIN POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2001-06-14 | — | — | WO | disclosed |