Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | TDP2 | O95551 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30832650 | 1.00 | APAF1 (0.43) | APAF1TDP2NSD2HKDC1ALDH1A1 | |
| SCHEMBL6904573 | 0.98 | APAF1 (0.46) | APAF1TDP2NSD2HKDC1ALDH1A1 | |
| SCHEMBL8244044 | 0.85 | DRD2 (0.48) | TDP2NSD2MAPTMAPK1EGFR | |
| SCHEMBL8796353 | 0.83 | MEN1 (0.49) | APAF1TDP2NSD2HKDC1ALDH1A1 | |
| SCHEMBL687468 | 0.82 | ALDH1A1 (0.44) | ALDH1A1MAPTMAPK1L3MBTL1KDM4E | |
| SCHEMBL669617 | 0.81 | APAF1 (0.41) | APAF1TDP2NSD2HKDC1ALDH1A1 | |
| SCHEMBL686641 | 0.80 | ALDH1A1 (0.42) | ALDH1A1MAPTMAPK1EGFRL3MBTL1 | |
| Lithium SCHEMBL686643 | 0.80 | ALDH1A1 (0.42) | ALDH1A1MAPTMAPK1EGFRL3MBTL1 | |
| SCHEMBL11620336 | 0.79 | APAF1 (0.44) | APAF1TDP2NSD2HKDC1ALDH1A1 | |
| SCHEMBL28018501 | 0.79 | APAF1 (0.38) | APAF1TDP2NSD2HKDC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240392044-A1 | OLEFIN POLYMERIZATION CATALYST SYSTEM AND POLYMERIZATION PROCESS | NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) | 2024-11-28 | — | — | US | disclosed |
| EP-4405367-A1 | OLEFIN POLYMERIZATION CATALYST SYSTEM AND POLYMERIZATION PROCESS | Nova Chemicals (International) S.A. (CH) | 2024-07-31 | — | — | EP | disclosed |
| CN-117980314-A | Olefin polymerization catalyst system and polymerization process | 诺瓦化学品(国际)股份有限公司 | 2024-05-03 | — | — | CN | disclosed |
| WO-2023042155-A1 | OLEFIN POLYMERIZATION CATALYST SYSTEM AND POLYMERIZATION PROCESS | NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) | 2023-03-23 | — | — | WO | disclosed |
| US-7060710-B2 | Isoxazole pyrazoloindane derivatives as cognition enhancing GABAA α5 subtype ligands | MERCK SHARP & DOHME LTD. (GB) | 2006-06-13 | — | — | US | disclosed |
| EP-1501843-A1 | ALKARYL-SUBSTITUTED GROUP 4 METAL COMPLEXES, CATALYSTS AND OLEFIN POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2005-02-02 | — | — | EP | disclosed |
| US-6825295-B2 | COORDINATION POLYMERIZATION CATALYST | DOW GLOBAL TECHNOLOGIES INC. | 2004-11-30 | — | — | US | disclosed |
| EP-0923589-B1 | 3-HETEROATOM SUBSTITUTED CYCLOPENTADIENYL-CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES INC (US) | 2004-09-15 | — | — | EP | disclosed |
| WO-2004044018-A2 | PROCESS FOR HOMO- OR COPOLYMERIZATION OF CONJUGATED DIENES AND IN SITU FORMATION OF POLYMER BLENDS AND PRODUCTS MADE THEREBY | DOW GLOBAL TECHNOLOGIES, INC. (US) | 2004-05-27 | — | — | WO | disclosed |
| US-20040006226-A1 | Isoxazole pyrazoloindane derivatives as cognition enhancing GABA-A alpha 5 subtype ligands | MERCK SHARP & DOHME LTD. (GB) | 2004-01-08 | — | — | US | disclosed |
| WO-2003091265-A1 | ALKARYL-SUBSTITUTED GROUP 4 METAL COMPLEXES, CATALYSTS AND OLEFIN POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-11-06 | — | — | WO | disclosed |
| US-6515155-B1 | Group 4 metal complexes of the constrained geometry type, catalysts derived therefrom and polymerization processes using the same, characterized by a nitrogen containing aliphatic or cycloaliphatic moiety that is substituted with one or more | DOW GLOBAL TECHNOLOGIES INC. | 2003-02-04 | — | — | US | disclosed |
| US-20030004286-A1 | Alkaryl-substituted Group 4 metal complexes, catalysts and olefin polymerization process | DOW GLOBAL TECHNOLOGIES LLC | 2003-01-02 | — | — | US | disclosed |
| US-20020165329-A1 | Heat-resistant group 4 metal metallecenes having a nitrogen with aliphatic or cycloaliphatic moiety substituted with aryl group(s)and a silane bridge; high-molecular weight ethylene-alpha olefin copolymers; high concentration of comonomer | KLOSIN JERZY (US) | 2002-11-07 | — | — | US | disclosed |
| EP-1253158-A1 | Substituted group 4 metal complexes, catalysts and olefin polymerization process | DOW GLOBAL TECHNOLOGIES INC. (US) | 2002-10-30 | — | — | EP | disclosed |
| EP-1242471-A1 | SUBSTITUTED GROUP 4 METAL COMPLEXES, CATALYSTS AND OLEFIN POLYMERIZATION PROCESS | THE DOW CHEMICAL COMPANY (US) | 2002-09-25 | — | — | EP | disclosed |
| US-6268444-B1 | TITANIUM, ZIRCONIUM OR HAFNIUM COMPOUNDS FOR POLYMERIZATION | DOW CHEMICAL COMPANY | 2001-07-31 | — | — | US | disclosed |
| WO-2001042315-A1 | SUBSTITUTED GROUP 4 METAL COMPLEXES, CATALYSTS AND OLEFIN POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2001-06-14 | — | — | WO | disclosed |
| EP-0923589-A1 | 3-HETEROATOM SUBSTITUTED CYCLOPENTADIENYL-CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS | THE DOW CHEMICAL COMPANY (US) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998006727-A1 | 3-HETEROATOM SUBSTITUTED CYCLOPENTADIENYL-CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS | THE DOW CHEMICAL COMPANY (US) | 1998-02-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040006226-A1 | Isoxazole pyrazoloindane derivatives as cognition enhancing GABA-A alpha 5 subtype ligands | GABRA5, GABRB1, GABRA4 | APAF1 4111/4885TDP2 2684/4885NSD2 2618/4885 |
| US-20020165329-A1 | Heat-resistant group 4 metal metallecenes having a nitrogen with aliphatic or cycloaliphatic moiety substituted with aryl group(s)and a silane bridge; high-molecular weight ethylene-alpha olefin copolymers; high concentration of comonomer | B2M, WEE2, WASF2 | APAF1 3532/4885TDP2 4739/4885NSD2 4351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.