SCHEMBL6866672

SCHEMBL6866672

Cc1ccc(NS(=O)(=O)N(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.61
MEN1 O00255 2/20 0.61
KMT2A Q03164 2/20 0.61
CA1 P00915 2/20 0.53
CA2 P00918 2/20 0.53
CA12 O43570 2/20 0.53
CA9 Q16790 2/20 0.53
GAA P10253 1/20 0.51
NR3C2 P08235 4/20 0.50
FFAR1 O14842 1/20 0.47
ALDH1A1 P00352 2/20 0.47
LMNA P02545 2/20 0.47
MAPT P10636 2/20 0.47
MCL1 Q07820 2/20 0.47
MAPK1 P28482 1/20 0.47
GFER P55789 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
HTT P42858 1/20 0.47
KEAP1 Q14145 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29223932 0.86 KEAP1 (0.52) HPGDMEN1KMT2ACA1CA2
SCHEMBL3467606 0.76 HPGD (1.00) HPGDMEN1KMT2ACA1CA2
SCHEMBL7074889 0.73 ALDH1A1 (0.51) HPGDMEN1KMT2ACA12CA9
SCHEMBL3697451 0.73 PKM (0.71) KMT2ACA12CA9ALDH1A1MAPT
SCHEMBL806766 0.73 CA12 (0.85) HPGDMEN1KMT2ACA1CA2
SCHEMBL15741207 0.73 CA12 (0.69) HPGDMEN1KMT2ACA1CA2
Hydrochloric Acid SCHEMBL27734751 0.72 CA12 (0.82) HPGDMEN1KMT2ACA1CA2
SCHEMBL13294987 0.72 HPGD (0.63) HPGDMEN1KMT2ACA1CA2
SCHEMBL28634601 0.72 ALDH1A1 (0.66) KMT2ACA12CA9ALDH1A1MAPT
SCHEMBL28645206 0.71 CA1 (0.61) HPGDMEN1KMT2ACA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1412412-A2 MELT POLYCARBONATE EXHIBITING AN IMPROVED RESISTANCE TO HYDROLYSIS Bayer MaterialScience AG (DE) 2004-04-28 EP disclosed
EP-1377624-A1 POLYCARBONATE HAVING A LOW SHEAR THINNING RATIO Bayer Aktiengesellschaft (DE) 2004-01-07 EP disclosed
WO-2002077101-A2 MELT POLYCARBONATE EXHIBITING AN IMPROVED RESISTANCE TO HYDROLYSIS BAYER AKTIENGESELLSCHAFT (DE) 2002-10-03 WO disclosed
WO-2002077064-A1 POLYCARBONATE HAVING A LOW SHEAR THINNING RATIO BAYER AKTIENGESELLSCHAFT (DE) 2002-10-03 WO disclosed