SCHEMBL686694

SCHEMBL686694

C=C(C)C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.59
FOLH1 Q04609 2/20 0.55
SLC6A5 Q9Y345 1/20 0.47
GSR P00390 1/20 0.43
CPB2 Q96IY4 10/20 0.42
RNPEP Q9H4A4 1/20 0.42
SIRT6 Q8N6T7 1/20 0.41
SIRT1 Q96EB6 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
MMP2 P08253 1/20 0.40
MMP9 P14780 1/20 0.40
GNPAT O15228 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1690444 1.00 TGFBR1 (0.59) TGFBR1FOLH1SLC6A5GSRCPB2
SCHEMBL6579582 1.00 TGFBR1 (0.59) TGFBR1FOLH1SLC6A5GSRCPB2
SCHEMBL31571912 0.95 TGFBR1 (0.61) TGFBR1FOLH1SLC6A5GSRCPB2
SCHEMBL31571914 0.93 TGFBR1 (0.59) TGFBR1FOLH1SLC6A5GSRCPB2
SCHEMBL5013249 0.90 FOLH1 (0.50) TGFBR1FOLH1SLC6A5GSRCPB2
SCHEMBL5013251 0.90 FOLH1 (0.50) TGFBR1FOLH1SLC6A5GSRCPB2
SCHEMBL8376832 0.87 TGFBR1 (0.46) TGFBR1FOLH1SLC6A5GSRCPB2
SCHEMBL1455722 0.86 FOLH1 (0.58) TGFBR1FOLH1SLC6A5GSRCPB2
SCHEMBL1455716 0.86 FOLH1 (0.58) TGFBR1FOLH1SLC6A5GSRCPB2
SCHEMBL31243301 0.84 TGFBR1 (0.44) TGFBR1FOLH1SLC6A5GSRCPB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 391 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114096514-B Polymerizable amino acid-based compounds and ophthalmic devices made therefrom 强生视力健公司 2025-06-17 CN claimed
CN-119060329-B Enzyme response polyamino acid, self-adaptive bionic mechanical gradient hydrogel and preparation method and application thereof 中国科学院长春应用化学研究所 2025-03-07 CN claimed
CN-119060329-A Enzyme response polyamino acid, self-adaptive bionic mechanical gradient hydrogel and preparation method and application thereof 中国科学院长春应用化学研究所 2024-12-03 CN claimed
EP-4165015-B9 AMINO ACID-BASED POLYMERIZABLE COMPOUNDS AND OPHTHALMIC DEVICES PREPARED THEREFROM JOHNSON AND JOHNSON VISION CARE INC (US) 2024-11-27 EP claimed
CN-115427746-B Use of a coating composition to make a substrate frost resistant, composition and method therefor 西恩斯科公司 2024-11-22 CN claimed
EP-4165015-B1 AMINO ACID-BASED POLYMERIZABLE COMPOUNDS AND OPHTHALMIC DEVICES PREPARED THEREFROM JOHNSON AND JOHNSON VISION CARE INC (US) 2024-08-07 EP claimed
CN-118236297-A Polyphenol moisturizing skin care lotion and preparation method thereof 费米善(丽水)科技有限公司 2024-06-25 CN claimed
CN-114702700-B Preparation method of anticoagulant filler for blood perfusion device 江苏恰瑞生物科技有限公司 2023-11-21 CN claimed
WO-2023116955-A1 WATER-BORNE HYBRID VARNISH AND THE METHOD OF ITS PREPARATION Centrum organické chemie s.r.o. (CZ) 2023-06-29 WO claimed
US-20230183515-A1 COATING COMPOSITION, USE AND METHODS FOR MAKING A SUBSTRATE FROST RESISTANT SOLVAY SA (BE) 2023-06-15 US claimed
WO-2011031453-A1 METHOD OF CHEMICALLY MODIFYING THE INTERNAL REGION OF A HAIR SHAFT THE PROCTER & GAMBLE COMPANY (US) 2011-03-17 WO claimed
EP-2295029-A1 Method of chemically modifying the internal region of a hair shaft The Procter & Gamble Company (US) 2011-03-16 EP claimed
US-20100003210-A1 EXTERNAL SKIN AGENT COMPRISING MODIFIED CLAY FOR PREVENTING INFLAMMATION POLA CHEMICAL INDUSTRIES INC. (JP) 2010-01-07 US claimed
US-20090022681-A1 Hair Care Composition THE PROCTER & GAMBLE COMPANY 2009-01-22 US claimed
WO-2008055482-A1 CONTACT LENS MATERIAL WOEHLK CONTACT-LINSEN GMBH (DE) 2008-05-15 WO claimed
WO-2007127722-A2 SURFACE-MODIFIED SUBSTRATE AND METHOD OF ITS PREPARATION RENSSELAER POLYTECHNIC INSTITUTE (US) 2007-11-08 WO claimed
EP-1846010-A1 EXTERNAL SKIN AGENT COMPRISING MODIFIED CLAY FOR PREVENTING INFLAMMATION Pola Chemical Industries Inc. (JP) 2007-10-24 EP claimed
WO-2006067945-A1 EXTERNAL SKIN AGENT COMPRISING MODIFIED CLAY FOR PREVENTING INFLAMMATION POLA CHEMICAL INDUSTRIES INC. (JP) 2006-06-29 WO claimed
EP-0225503-B1 RESOLUTION SYSTEM YEDA RESEARCH AND DEVELOPMENT COMPANY LIMITED (IL) 1989-08-02 EP claimed
EP-0225503-A1 Resolution system YEDA RESEARCH AND DEVELOPMENT COMPANY LIMITED (IL) 1987-06-16 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090022681-A1 Hair Care Composition MTR, SUCLG1, MUC1 TGFBR1 2595/4885FOLH1 2095/4885SLC6A5 4256/4885
US-20100003210-A1 EXTERNAL SKIN AGENT COMPRISING MODIFIED CLAY FOR PREVENTING INFLAMMATION CUTA, TSLP, NFKBIA TGFBR1 1346/4885FOLH1 3951/4885SLC6A5 2638/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.