Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6869675 | 0.91 | ALDH1A1 (0.54) | HTTTP53LMNAMAPTHPGD | |
| SCHEMBL6870631 | 0.89 | LMNA (0.48) | HTTTP53LMNAMAPTHPGD | |
| SCHEMBL7114944 | 0.87 | ADORA2A (0.54) | HTTTP53LMNAMAPTHPGD | |
| SCHEMBL6863761 | 0.87 | HPGD (0.46) | HTTTP53LMNAMAPTHPGD | |
| SCHEMBL6872062 | 0.86 | TP53 (0.47) | HTTTP53LMNAMAPTHPGD | |
| SCHEMBL6871570 | 0.85 | HPGD (0.46) | HTTTP53LMNAMAPTHPGD | |
| SCHEMBL6873996 | 0.85 | ADORA2A (0.55) | HTTTP53LMNAMAPTHPGD | |
| SCHEMBL6863739 | 0.85 | SMN1; SMN2 (0.54) | TP53LMNAMAPTHPGDGAA | |
| SCHEMBL6870074 | 0.85 | KMT2A (0.48) | LMNAMAPTHPGDALDH1A1MEN1 | |
| SCHEMBL6872927 | 0.85 | TP53 (0.46) | HTTTP53LMNAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347974-B1 | AMINOTRIAZOLOPYRIDIINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 2004-11-03 | — | — | EP | disclosed |