Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 15/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6871212 | 0.81 | ALDH1A1 (0.48) | ADORA2AMAPTNPC1RAB9A | |
| SCHEMBL6863761 | 0.80 | HPGD (0.46) | MAPT | |
| SCHEMBL6870753 | 0.80 | ADORA2A (0.37) | ADORA2A | |
| SCHEMBL6870751 | 0.79 | ADORA2A (0.41) | ADORA2A | |
| SCHEMBL6872919 | 0.78 | KDM4A (0.52) | ADORA2AMAPT | |
| SCHEMBL6870583 | 0.77 | ADORA2A (0.66) | ADORA2AMAPTNPC1RAB9A | |
| SCHEMBL6869047 | 0.77 | ADORA2A (0.40) | ADORA2ACDK8MAPTNPC1RAB9A | |
| SCHEMBL6867888 | 0.77 | ADORA2A (0.66) | ADORA2A | |
| SCHEMBL6867379 | 0.77 | ADORA2A (0.66) | ADORA2A | |
| SCHEMBL6867645 | 0.76 | POLB (0.49) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347974-B1 | AMINOTRIAZOLOPYRIDIINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 2004-11-03 | — | — | EP | disclosed |