Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 15/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7142283 | 0.87 | ALOX15 (0.43) | ADORA2ANAMPTKDM4EALDH1A1HPGD | |
| SCHEMBL6868263 | 0.82 | MAPT (0.46) | ADORA2ANAMPTALDH1A1NPC1MAPT | |
| SCHEMBL6867146 | 0.81 | ADORA2A (0.62) | ADORA2AKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL6871212 | 0.81 | ALDH1A1 (0.48) | ADORA2AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6871320 | 0.80 | SMN1; SMN2 (0.43) | ADORA2ANAMPTKDM4EALDH1A1HPGD | |
| SCHEMBL6868324 | 0.80 | NAMPT (0.46) | ADORA2ANAMPTKDM4EALDH1A1HPGD | |
| SCHEMBL6868261 | 0.79 | NPC1 (0.48) | ADORA2AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7703259 | 0.78 | ALDH1A1 (0.42) | ADORA2ANAMPTKDM4EALDH1A1HPGD | |
| SCHEMBL6872919 | 0.78 | KDM4A (0.52) | ADORA2AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6867096 | 0.77 | TP53 (0.44) | KDM4EALDH1A1HPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347974-B1 | AMINOTRIAZOLOPYRIDIINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 2004-11-03 | — | — | EP | disclosed |