Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 10/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7145420 | 0.85 | KDM4A (0.48) | KDM4AMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL6871212 | 0.84 | ALDH1A1 (0.48) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL6870436 | 0.81 | ADORA2A (0.61) | MAPTALDH1A1HPGDADORA2ASMN1; SMN2 | |
| SCHEMBL6867379 | 0.80 | ADORA2A (0.66) | ADORA2AKDM4E | |
| SCHEMBL6872186 | 0.79 | SMN1; SMN2 (0.43) | HPGDADORA2ASMN1; SMN2 | |
| SCHEMBL6871339 | 0.79 | ADORA2A (0.68) | ALDH1A1GAAADORA2ASMN1; SMN2KDM4E | |
| SCHEMBL6867704 | 0.78 | ADORA2A (0.67) | ALDH1A1HPGDGAAADORA2ASMN1; SMN2 | |
| SCHEMBL6867472 | 0.78 | ADORA2A (0.40) | MAPTADORA2A | |
| SCHEMBL6869047 | 0.78 | ADORA2A (0.40) | MAPTALDH1A1HPGDADORA2ASMN1; SMN2 | |
| SCHEMBL6870583 | 0.78 | ADORA2A (0.66) | MAPTMEN1KMT2APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347974-B1 | AMINOTRIAZOLOPYRIDIINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 2004-11-03 | — | — | EP | disclosed |