Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 18/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6873039 | 0.88 | ADORA2A (0.66) | ADORA2A | |
| SCHEMBL6869733 | 0.88 | ADORA2A (0.52) | ADORA2AHPGD | |
| SCHEMBL6871448 | 0.87 | ADORA2A (0.65) | ADORA2A | |
| SCHEMBL6871451 | 0.82 | ADORA2A (0.66) | ADORA2A | |
| SCHEMBL6870443 | 0.81 | LMNA (0.45) | ADORA2AHPGDSMN1; SMN2 | |
| SCHEMBL6872383 | 0.81 | ADORA2A (0.56) | ADORA2A | |
| SCHEMBL6868095 | 0.81 | KDM4E (0.53) | ADORA2AHPGDSMN1; SMN2 | |
| SCHEMBL6873028 | 0.80 | ADORA2A (0.73) | ADORA2A | |
| SCHEMBL6870459 | 0.80 | ADORA2A (0.43) | ADORA2AHPGDSMN1; SMN2 | |
| SCHEMBL6870649 | 0.79 | ADORA2A (0.61) | ADORA2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347974-B1 | AMINOTRIAZOLOPYRIDIINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 2004-11-03 | — | — | EP | disclosed |