Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 10/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | NAAA | Q02083 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.42 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexylamine SCHEMBL6867493 | 0.92 | SIGMAR1 (0.47) | EPHX1SIGMAR1NAAAEPHX2GNAI3 | |
| Cyclohexylamine SCHEMBL6864737 | 0.86 | ALDH1A1 (0.52) | EPHX1NAAAEPHX2GNAI3GNAO1 | |
| Cyclohexylamine SCHEMBL6864148 | 0.86 | ALDH1A1 (0.52) | EPHX1NAAAEPHX2GNAI3GNAO1 | |
| Octane SCHEMBL27874847 | 0.85 | GNAI3 (0.52) | EPHX1SIGMAR1NAAAEPHX2GNAI3 | |
| Cyclohexylamine SCHEMBL6868335 | 0.84 | SIGMAR1 (0.41) | EPHX1SIGMAR1NAAAENPP2 | |
| Cyclohexylamine SCHEMBL588721 | 0.83 | CYP1A2 (0.50) | EPHX1SIGMAR1NAAAGNAI3GNAO1 | |
| SCHEMBL20484398 | 0.81 | SIGMAR1 (0.63) | EPHX1SIGMAR1NAAAEPHX2GNAI3 | |
| Cyclohexylamine SCHEMBL29057250 | 0.79 | CYP1A2 (0.50) | NAAAGNAI3GNAO1GNAI1ENPP2 | |
| SCHEMBL25282168 | 0.78 | ALDH1A1 (0.56) | EPHX1NAAAGNAI3GNAO1GNAI1 | |
| Cyclohexylamine SCHEMBL6865056 | 0.78 | DNM1 (0.56) | EPHX1SIGMAR1NAAAGNAI3GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6806289-B1 | SUCH AS AMMINE (2-AMINO-3-PICOLINE) DICHLOROPLATINUM(II); EFFICIENCY AND SELECTIVITY FOR DESTROYING TRANSFORMED CELLS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-10-19 | — | — | US | disclosed |