Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexylamine SCHEMBL6867493 | 0.87 | SIGMAR1 (0.47) | SIGMAR1EPHX1MMP8MMP2CYP1A2 | |
| Cyclohexylamine SCHEMBL6868158 | 0.84 | EPHX1 (0.58) | SIGMAR1EPHX1NAAAENPP2 | |
| Cyclohexylamine SCHEMBL7039293 | 0.83 | MMP8 (0.38) | SIGMAR1EPHX1ALDH1A1MMP8MMP2 | |
| Cyclohexylamine SCHEMBL2067439 | 0.80 | CYP1A2 (0.42) | ALDH1A1MMP8MMP2MMP1CYP1A2 | |
| Cyclohexane SCHEMBL11024994 | 0.80 | EPHX1 (0.45) | SIGMAR1EPHX1ALDH1A1KDM4E | |
| Cyclohexylamine SCHEMBL4447887 | 0.77 | SHBG (0.39) | ALDH1A1MMP8MMP2MMP1CYP1A2 | |
| Cyclohexylamine SCHEMBL4239622 | 0.77 | THRB (0.39) | ALDH1A1MMP8MMP2MMP1 | |
| Cyclohexylamine SCHEMBL4751057 | 0.77 | EPHX1 (0.34) | EPHX1ALDH1A1KDM4EMMP8MMP2 | |
| Cyclohexylamine SCHEMBL28097700 | 0.76 | TSHR (0.44) | EPHX1ALDH1A1CYP1A2NAAA | |
| Cyclohexylamine SCHEMBL588721 | 0.75 | CYP1A2 (0.50) | SIGMAR1EPHX1CYP1A2NAAAENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6806289-B1 | SUCH AS AMMINE (2-AMINO-3-PICOLINE) DICHLOROPLATINUM(II); EFFICIENCY AND SELECTIVITY FOR DESTROYING TRANSFORMED CELLS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-10-19 | — | — | US | disclosed |