Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 7/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 3/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6869114 | 1.00 | ADRA2A (0.38) | ADRA2AMCHR1MEN1KMT2AMAPK1 | |
| SCHEMBL6868701 | 0.88 | LMNA (0.45) | ADRA2AMCHR1MEN1KMT2ARAB9A | |
| SCHEMBL6868693 | 0.88 | LMNA (0.45) | ADRA2AMCHR1MEN1KMT2ARAB9A | |
| SCHEMBL6875125 | 0.86 | SMN1; SMN2 (0.42) | ADRA2AMCHR1MEN1KMT2ARAB9A | |
| SCHEMBL6875121 | 0.86 | SMN1; SMN2 (0.42) | ADRA2AMCHR1MEN1KMT2ARAB9A | |
| SCHEMBL6878621 | 0.86 | SMN1; SMN2 (0.45) | ADRA2AMCHR1MEN1KMT2AMAPK1 | |
| SCHEMBL6878625 | 0.86 | SMN1; SMN2 (0.45) | ADRA2AMCHR1MEN1KMT2AMAPK1 | |
| SCHEMBL6876262 | 0.83 | SMN1; SMN2 (0.55) | ADRA2AMCHR1MEN1KMT2AMAPK1 | |
| SCHEMBL6871842 | 0.83 | SMN1; SMN2 (0.55) | ADRA2AMCHR1MEN1KMT2ARAB9A | |
| SCHEMBL6871841 | 0.83 | SMN1; SMN2 (0.55) | ADRA2AMCHR1MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |