Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3477821 | 0.77 | TLR4 (0.35) | — | |
| SCHEMBL12835081 | 0.76 | TLR4 (0.33) | — | |
| SCHEMBL6907548 | 0.75 | TLR4 (0.34) | — | |
| SCHEMBL7889368 | 0.74 | METAP1 (0.38) | METAP1CCR6 | |
| SCHEMBL13899831 | 0.74 | — | — | |
| SCHEMBL443868 | 0.73 | TLR4 (0.33) | — | |
| SCHEMBL3965498 | 0.73 | METAP1 (0.41) | METAP1CCR6 | |
| SCHEMBL9956733 | 0.72 | CRBN (0.36) | METAP1 | |
| SCHEMBL6865770 | 0.71 | HTR6 (0.39) | METAP1CCR6 | |
| SCHEMBL4631245 | 0.71 | HTR6 (0.39) | METAP1CCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1069106-B1 | Dimethyl-(3-aryl-but-3-enyl) amine derivatives with analgesic activity | GRUENENTHAL GMBH (DE) | 2004-01-28 | — | — | EP | disclosed |
| EP-0799819-B1 | 1-Dimethylaminomethyl 2-phenyl cycloalk-2-ene derivatives with analgesic activity | GRUENENTHAL GMBH (DE) | 2002-09-11 | — | — | EP | disclosed |
| US-RE37355-E1 | 6-dimethylaminomethyl-1-phenyl-cyclohexane compounds as pharmaceutical active ingredients | GRUENENTHAL GMBH (DE) | 2001-09-04 | — | — | US | disclosed |
| EP-1069106-A2 | Dimethyl-(3-aryl-but-3-enyl) amine derivatives with analgesic activity | Grünenthal GmbH (DE) | 2001-01-17 | — | — | EP | disclosed |
| EP-0983994-A2 | Pharmaceutically-active dimethyl-(3-aryl-but-3-enyl)-amine compounds | Grünenthal GmbH (DE) | 2000-03-08 | — | — | EP | disclosed |
| EP-0753506-B1 | 6-Dimethylaminomethyl-1-phenyl-cyclo-hexane compounds as pharmaceutical agents | GRUENENTHAL GMBH (DE) | 1999-08-18 | — | — | EP | disclosed |
| US-5811582-A | ANALGESICS | GRUENENTHAL GMBH (DE) | 1998-09-22 | — | — | US | disclosed |
| US-5733936-A | ANALGESICS | GRUENENTHAL GMBH (DE) | 1998-03-31 | — | — | US | disclosed |
| EP-0799819-A1 | Dimethyl-(3-aryl-but-3-enyl) amine derivatives with analgesic activity | Grünenthal GmbH (DE) | 1997-10-08 | — | — | EP | disclosed |
| EP-0753506-A1 | 6-Dimethylaminomethyl-1-phenyl-cyclo-hexane compounds as pharmaceutical agents | Grünenthal GmbH (DE) | 1997-01-15 | — | — | EP | disclosed |