Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA known ✓ | P35790 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL1227449 | 0.82 | LMNA (0.36) | ALDH1A1KDM4ELMNAHTTSMN1; SMN2 | |
| Bromide SCHEMBL6873657 | 0.81 | GGPS1 (0.35) | ALDH1A1KDM4ERAB9ALMNAHTT | |
| SCHEMBL1226946 | 0.80 | ACP3 (0.35) | ALDH1A1KDM4ELMNAHTTSMN1; SMN2 | |
| Bromide SCHEMBL3361424 | 0.80 | ALDH1A1 (0.51) | ALDH1A1KDM4ERAB9ACHKALMNA | |
| Hydrochloric Acid SCHEMBL2260159 | 0.80 | ALDH1A1 (0.49) | ALDH1A1KDM4ERAB9ACHKALMNA | |
| Hydrochloric Acid SCHEMBL2259515 | 0.79 | KDM4E (0.34) | ALDH1A1KDM4ERAB9A | |
| Hydrochloric Acid SCHEMBL1227055 | 0.78 | ACP3 (0.34) | ALDH1A1KDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL13851328 | 0.78 | ALDH1A1 (0.53) | ALDH1A1KDM4ERAB9ACHKALMNA | |
| Benzyl Viologen SCHEMBL4079047 | 0.76 | ALDH1A1 (0.71) | ALDH1A1KDM4ERAB9ACHKALMNA | |
| Bromide SCHEMBL2462792 | 0.76 | SLC6A4 (0.41) | ALDH1A1KDM4ELMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040252099-A1 | Displays for high resolution images and methods for producing same | NTERA LIMITED (IE) | 2004-12-16 | — | — | US | disclosed |
| EP-1428066-A2 | DISPLAYS FOR HIGH RESOLUTION IMAGES AND METHODS FOR PRODUCING SAME | Ntera Limited (IE) | 2004-06-16 | — | — | EP | disclosed |
| WO-2003001288-A2 | DISPLAYS FOR HIGH RESOLUTION IMAGES AND METHODS FOR PRODUCING SAME | NTERA LIMITED (IE) | 2003-01-03 | — | — | WO | disclosed |
| EP-1271227-A1 | Electrochromic display for high resolution and method of producing the same | Nanomat Limited (IE) | 2003-01-02 | — | — | EP | disclosed |