Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 3/20 | 0.33 |
| ▸ | MMP8 | P22894 | 4/20 | 0.32 |
| ▸ | MMP14 | P50281 | 4/20 | 0.32 |
| ▸ | MMP1 | P03956 | 3/20 | 0.32 |
| ▸ | MMP2 | P08253 | 3/20 | 0.32 |
| ▸ | MMP3 | P08254 | 3/20 | 0.32 |
| ▸ | MMP7 | P09237 | 3/20 | 0.32 |
| ▸ | MMP9 | P14780 | 3/20 | 0.32 |
| ▸ | MMP13 | P45452 | 3/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | PGK1 | P00558 | 2/20 | 0.31 |
| ▸ | PGK2 | P07205 | 2/20 | 0.31 |
| ▸ | FDPS | P14324 | 2/20 | 0.31 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1226946 | 0.98 | ACP3 (0.35) | ACP3ALDH1A1LMNAHTTSMN1; SMN2 | |
| Bromide SCHEMBL1227449 | 0.96 | LMNA (0.36) | ACP3ALDH1A1LMNAHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6442055 | 0.89 | PABPC1 (0.43) | LMNAFDPSGGPS1 | |
| Bromide SCHEMBL2462792 | 0.89 | SLC6A4 (0.41) | ALDH1A1LMNAHTTSMN1; SMN2KDM4E | |
| Bromide SCHEMBL6873657 | 0.84 | GGPS1 (0.35) | ALDH1A1LMNAHTTSMN1; SMN2KDM4E | |
| Bromide SCHEMBL6874660 | 0.84 | KDM4E (0.31) | ALDH1A1LMNAHTTSMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL2263262 | 0.84 | MMP8 (0.36) | ALDH1A1LMNAHTTSMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL2266110 | 0.83 | ACP3 (0.35) | ACP3ALDH1A1LMNAHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2264607 | 0.83 | MMP2 (0.37) | MMP8MMP14MMP1MMP2MMP3 | |
| Hydrochloric Acid SCHEMBL3930213 | 0.83 | FDPS (0.32) | ALDH1A1LMNAHTTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1004143-B1 | CHARGE GENERATORS IN HETEROLAMELLAR MULTILAYER THIN FILMS | UNIV SOUTHERN CALIFORNIA (US) | 2012-09-05 | — | — | EP | disclosed |
| EP-2287937-A2 | Charge generators in heterolamellar multilayer thin films | The University of Southern California (US) | 2011-02-23 | — | — | EP | disclosed |
| EP-0871985-B1 | HETEROLAMELLAR PHOTOVOLTAIC FILMS | UNIV PRINCETON (US) | 2009-08-19 | — | — | EP | disclosed |
| EP-1386884-B1 | Process for production of hydrogen peroxide by direct synthesis from hydrogen and oxygen | UNIV PRINCETON (US) | 2007-03-07 | — | — | EP | disclosed |
| EP-1004143-A4 | CHARGE GENERATORS IN HETEROLAMELLAR MULTILAYER THIN FILMS | UNIV SOUTHERN CALIFORNIA (US) | 2006-04-12 | — | — | EP | disclosed |
| EP-1394185-B1 | Derivative of polyvinylpyridine | UNIV PRINCETON (US) | 2005-08-24 | — | — | EP | disclosed |
| EP-1394185-A1 | Derivative of polyvinylpyridine | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2004-03-03 | — | — | EP | disclosed |
| EP-1386884-A1 | Electron acceptor compositions on polymer templates and catalytic production of hydrogen peroxide | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2004-02-04 | — | — | EP | disclosed |
| EP-0846082-B1 | ELECTRON ACCEPTOR COMPOSITIONS ON POLYMER TEMPLATES AND CATALYTIC PRODUCTION OF HYDROGEN PEROXIDE | UNIV PRINCETON (US) | 2003-10-08 | — | — | EP | disclosed |
| EP-0713492-B1 | ELECTRON ACCEPTOR COMPOSITIONS | UNIV PRINCETON (US) | 2001-07-18 | — | — | EP | disclosed |
| US-6187871-B1 | DECOMPOSITION OF WATER; CATALYST | THE TRUSTEES OF PRINCETON UNIVERSITY | 2001-02-13 | — | — | US | disclosed |
| US-6107561-A | A PHOTOVOLTAIC CELL COMPRISING REDOX SYSTEMS FOR PRODUCTION OF HYDROGEN PEROXIDE FROM OXYGEN AND HYDROGEN GASES, THE PRODUCTION OF HYDROGEN GAS FROM WATER, AND THE REDUCTION OF KETONES TO FORM ALCOHOLS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2000-08-22 | — | — | US | disclosed |
| EP-1004143-A1 | CHARGE GENERATORS IN HETEROLAMELLAR MULTILAYER THIN FILMS | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2000-05-31 | — | — | EP | disclosed |
| US-5906892-A | GROUP VIII METAL COMPLEX ON SUPPORT | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1999-05-25 | — | — | US | disclosed |
| WO-1999003154-A1 | CHARGE GENERATORS IN HETEROLAMELLAR MULTILAYER THIN FILMS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 1999-01-21 | — | — | WO | disclosed |
| US-5695890-A | PHOTOELECTRODE COMPRISING CHARGE TRANSFER COMPLEX; REDOX CATALYSTS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1997-12-09 | — | — | US | disclosed |
| EP-0713492-A1 | ELECTRON ACCEPTOR COMPOSITIONS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1996-05-29 | — | — | EP | disclosed |
| US-5500297-A | PHOTOINDUCED CHARGE SEPARATION, ORGANIC PILLARS, REPEATING CATIONIC CENTERS AND METAL PHOSPHONATES WITH ENTRAPPED COLLOIDAL PARTICLES OF PALLADIUM OR PLATINUM | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1996-03-19 | — | — | US | disclosed |
| US-5480629-A | TREATING AN AQUEOUS SUSPENSION OF CATALYST WITH OXYGEN AND HYDROGEN SOURCES, SEPARATING THE CATALYST AND ISOLATING HYDROGEN PEROXIDE | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1996-01-02 | — | — | US | disclosed |
| WO-1995004743-A1 | ELECTRON ACCEPTOR COMPOSITIONS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1995-02-16 | — | — | WO | disclosed |