Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | TERT | O14746 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL1227449 | 0.88 | LMNA (0.36) | GGPS1KDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL1226946 | 0.86 | ACP3 (0.35) | GGPS1KDM4ELMNAHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1227055 | 0.84 | ACP3 (0.34) | GGPS1KDM4ELMNAHTTSMN1; SMN2 | |
| Bromide SCHEMBL2462792 | 0.81 | SLC6A4 (0.41) | KDM4ELMNAHTTSMN1; SMN2ALDH1A1 | |
| Bromide SCHEMBL6872242 | 0.81 | ALDH1A1 (0.50) | KDM4ELMNAHTTSMN1; SMN2RAB9A | |
| SCHEMBL2609279 | 0.78 | CYP2C19 (0.38) | GGPS1MEN1TP53CYP1A2CYP2D6 | |
| Bromide SCHEMBL6874660 | 0.77 | KDM4E (0.31) | KDM4ELMNAHTTSMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2259515 | 0.77 | KDM4E (0.34) | GGPS1KDM4ERAB9AALDH1A1 | |
| SCHEMBL9889761 | 0.76 | MEN1 (0.41) | GGPS1MEN1TP53CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL6442055 | 0.75 | PABPC1 (0.43) | GGPS1MAPTLMNAFDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040252099-A1 | Displays for high resolution images and methods for producing same | NTERA LIMITED (IE) | 2004-12-16 | — | — | US | disclosed |
| EP-1428066-A2 | DISPLAYS FOR HIGH RESOLUTION IMAGES AND METHODS FOR PRODUCING SAME | Ntera Limited (IE) | 2004-06-16 | — | — | EP | disclosed |
| WO-2003001288-A2 | DISPLAYS FOR HIGH RESOLUTION IMAGES AND METHODS FOR PRODUCING SAME | NTERA LIMITED (IE) | 2003-01-03 | — | — | WO | disclosed |
| EP-1271227-A1 | Electrochromic display for high resolution and method of producing the same | Nanomat Limited (IE) | 2003-01-02 | — | — | EP | disclosed |