Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.51 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CFD | P00746 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.45 |
| ▸ | PRKCG | P05129 | 2/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.45 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.45 |
| ▸ | MAP4K5 | Q9Y4K4 | 2/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6869746 | 0.88 | PLAU (0.43) | HPGDSCSNK1DPLAUHSD17B10KDM4E | |
| SCHEMBL6870074 | 0.86 | KMT2A (0.48) | CSNK1DKDM4EALDH1A1HPGDCYP2C19 | |
| SCHEMBL6863739 | 0.86 | SMN1; SMN2 (0.54) | KDM4EALDH1A1HPGDCYP2C19LMNA | |
| SCHEMBL6867628 | 0.86 | ADORA2A (0.60) | HPGDSPLAUHSD17B10KDM4EALDH1A1 | |
| SCHEMBL6863351 | 0.84 | PLAU (0.47) | PLAUHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL6868324 | 0.84 | NAMPT (0.46) | PLAUHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL6871493 | 0.83 | ADORA2A (0.66) | PLAUHPGDADORA2A | |
| SCHEMBL6867448 | 0.83 | HTT (0.56) | KDM4EALDH1A1HPGDLMNAROCK1 | |
| SCHEMBL6871404 | 0.83 | ADORA2A (0.51) | PLAUHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL6870096 | 0.83 | ADORA2A (0.60) | PLAUHSD17B10KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347974-B1 | AMINOTRIAZOLOPYRIDIINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 2004-11-03 | — | — | EP | disclosed |