Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6872215 | 0.90 | EGLN2 (0.42) | CSNK1DALDH1A1KDM4ETSHRKMT2A | |
| SCHEMBL6871283 | 0.90 | PTGER2 (0.44) | CSNK1DALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL6873157 | 0.88 | HPGDS (0.51) | PLAUCSNK1DALDH1A1HSD17B10KDM4E | |
| SCHEMBL6870707 | 0.87 | KMT2A (0.43) | ALDH1A1KMT2ALMNAADORA2AMAPT | |
| SCHEMBL6863096 | 0.87 | SMN1; SMN2 (0.43) | ALDH1A1HSD17B10KDM4EHPGDCYP2C19 | |
| SCHEMBL6869842 | 0.85 | PLAU (0.48) | PLAUALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL6870631 | 0.84 | LMNA (0.48) | ALDH1A1HSD17B10KDM4EHPGDCYP2C19 | |
| SCHEMBL6870530 | 0.82 | ADORA2A (0.43) | ALDH1A1HSD17B10KDM4EHPGDMEN1 | |
| SCHEMBL6863099 | 0.81 | ADORA2A (0.45) | ADORA2AMAP3K5 | |
| SCHEMBL6870638 | 0.80 | ADORA2A (0.55) | ALDH1A1HPGDMEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347974-B1 | AMINOTRIAZOLOPYRIDIINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 2004-11-03 | — | — | EP | disclosed |