Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR88 | Q9GZN0 | 6/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15127992 | 0.86 | GPR88 (0.52) | GPR88APP | |
| SCHEMBL1554247 | 0.79 | GPR88 (0.60) | GPR88HIF1ALMNATAS1R3TAS1R1 | |
| SCHEMBL15127998 | 0.79 | GPR88 (0.48) | GPR88APP | |
| SCHEMBL15121674 | 0.78 | GPR88 (0.50) | GPR88HIF1ATSHRMAPK1 | |
| SCHEMBL6871600 | 0.76 | SMN1; SMN2 (0.40) | GPR88HTTMAPK1RAB9A | |
| SCHEMBL2497363 | 0.73 | GPR88 (1.00) | GPR88 | |
| SCHEMBL11903449 | 0.73 | GPR88 (0.48) | GPR88HIF1ALMNATAS1R3TAS1R1 | |
| SCHEMBL6686922 | 0.73 | ALDH1A1 (0.61) | GPR88ERN1TSHRMAPK1KDM4E | |
| SCHEMBL12445601 | 0.73 | GAA (0.42) | GPR88HTTHIF1ALMNAGAA | |
| SCHEMBL6871594 | 0.71 | GPR88 (0.54) | GPR88 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011044195-A1 | MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-04-14 | — | — | WO | disclosed |